Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18260639 | 1.00 | GPR84 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL30413 | 1.00 | GPR84 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1273217 | 1.00 | GPR84 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5495040 | 1.00 | GPR84 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL45203 | 1.00 | GPR84 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL253962 | 1.00 | GPR84 (0.44) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5395520 | 0.98 | AKR1B1 (0.42) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1470099 | 0.91 | PPARG (0.53) | PPARGPPARDPPARATSHRPTPN1 | |
| SCHEMBL456745 | 0.91 | PPARG (0.53) | PPARGPPARDPPARATSHRPTPN1 | |
| SCHEMBL5418693 | 0.81 | GPR84 (0.36) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114642720-A | Pharmaceutical compositions of saposin C and methods of treating cancer | 百祥制药公司 | 2022-06-21 | — | — | CN | claimed |
| CN-111902133-B | Pharmaceutical compositions of saposin C and methods of treating cancer | 百祥制药公司 | 2022-04-15 | — | — | CN | claimed |
| CN-111902133-A | Pharmaceutical compositions of saposin C and methods of treating cancer | 百祥制药公司 | 2020-11-06 | — | — | CN | claimed |
| US-20070065369-A1 | NOVEL METHODS AND COMPOSITION FOR DELIVERING MACROMOLECULES TO OR VIA THE RESPIRATORY TRACT | NOVARTIS PHARMA AG (CH) | 2007-03-22 | — | — | US | claimed |
| US-7141236-B2 | Methods and compositions for delivering macromolecules to or via the respiratory tract | NEKTAR THERAPEUTICS (US) | 2006-11-28 | — | — | US | claimed |
| CN-114642720-A | Pharmaceutical compositions of saposin C and methods of treating cancer | 百祥制药公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-111902133-B | Pharmaceutical compositions of saposin C and methods of treating cancer | 百祥制药公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-111902133-A | Pharmaceutical compositions of saposin C and methods of treating cancer | 百祥制药公司 | 2020-11-06 | — | — | CN | disclosed |
| US-20070065369-A1 | NOVEL METHODS AND COMPOSITION FOR DELIVERING MACROMOLECULES TO OR VIA THE RESPIRATORY TRACT | NOVARTIS PHARMA AG (CH) | 2007-03-22 | — | — | US | disclosed |
| US-7141236-B2 | Methods and compositions for delivering macromolecules to or via the respiratory tract | NEKTAR THERAPEUTICS (US) | 2006-11-28 | — | — | US | disclosed |