SCHEMBL549057

SCHEMBL549057

CC(C)(C)ONC(=O)c1cccc([O])c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
RAB9A P51151 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
STAT3 P40763 1/20 0.39
KIF11 P52732 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 2/20 0.38
FURIN P09958 1/20 0.38
CYP2C19 P33261 1/20 0.37
MAPK1 P28482 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL549058 0.83 KDM4E (0.59) HDAC8HDAC6RAB9AKDM4EALDH1A1
SCHEMBL6647997 0.83 ALDH1A1 (0.51) HDAC8HDAC6RAB9ANPSR1KDM4E
SCHEMBL3297688 0.81 HDAC8 (0.46) HDAC8HDAC6RAB9ANPSR1KDM4E
SCHEMBL21051097 0.80 POLB (0.55) HDAC8HDAC6RAB9AALDH1A1SMN1; SMN2
SCHEMBL6188317 0.78 GRM5 (0.51) ALDH1A1
SCHEMBL159046 0.77 LMNA (0.52) RAB9AALDH1A1KMT2AMEN1LMNA
SCHEMBL6651205 0.77 ALDH1A1 (0.62) RAB9AALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL162858 0.76 HDAC8 (0.68) HDAC8HDAC6KDM4EALDH1A1KIF11
SCHEMBL165800 0.74 NPSR1 (0.61) HDAC8HDAC6NPSR1KDM4EALDH1A1
SCHEMBL55075 0.74 SLC7A5 (0.52) RAB9AALDH1A1STAT3NPC1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 543 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473335-B1 INK-JET RECORDING INK AND METHOD OF INK-JET RECORDING FUJIFILM CORP (JP) 2009-08-05 EP claimed
US-5110941-A Methods of producing 1H-pyraolo(5,1-c)-1,2,4-triazoles and pyrazole derivatives FUJI PHOTO FILM CO., LTD. (JP) 1992-05-05 US claimed
EP-3747963-B1 INK SET AND INKJET RECORDING METHOD FUJIFILM CORP (JP) 2024-05-29 EP disclosed
EP-3747963-A1 INK SET AND INKJET RECORDING METHOD Fujifilm Corporation (JP) 2020-12-09 EP disclosed
US-20200354599-A1 INK SET AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2020-11-12 US disclosed
EP-1408093-B1 COLORED IMAGE-FORMING COMPOSITIONS CONTAINING PHTHALOCYANINE COMPOUND, INKS, INKJET INKS, INKJET RECORDING METHOD AND METHOD OF IMPROVING TOLERANCE TO DECOLORATION DUE TO OZONE GAS FUJIFILM CORP (JP) 2018-02-21 EP disclosed
US-9528014-B2 Coloring composition, ink for inkjet recording using the coloring composition, method for inkjet recording using the ink for inkjet recording, ink cartridge, and inkjet recording material FUJIFILM CORPORATION (JP) 2016-12-27 US disclosed
EP-2778201-B1 COLOURED COMPOSITION AND INK FOR INKJET RECORDING FUJIFILM CORP (JP) 2016-04-06 EP disclosed
EP-2206750-B1 INK SET, INKJET RECORDING METHOD AND RECORDED MATTER FUJIFILM CORP (JP) 2016-01-13 EP disclosed
EP-2921530-A1 COLORING COMPOSITION, INK JET RECORDING INK USING COLORING COMPOSITION, INK JET RECORDING METHOD USING INK JET RECORDING INK, INK CARTRIDGE, AND INK JET RECORDING MATERIAL FUJIFILM Corporation (JP) 2015-09-23 EP disclosed
EP-2921531-A1 COLORING COMPOSITION, INK JET RECORDING INK, INK JET RECORDING METHOD, INK JET PRINTER CARTRIDGE, AND INK JET RECORDING MATERIAL Fujifilm Corporation (JP) 2015-09-23 EP disclosed
US-5145766-A Benzoyl esters or sulfonates CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
EP-0501468-A1 Silver halide color photographic photosensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1992-09-02 EP disclosed
EP-0491197-A1 Cyan image forming method and silver halide color photographic material containing cyan coupler FUJI PHOTO FILM CO., LTD. (JP) 1992-06-24 EP disclosed
EP-0488248-A1 Cyan image forming method and silver halide color photographic material containing cyan coupler FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0486965-A1 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-05-27 EP disclosed
US-5110941-A Methods of producing 1H-pyraolo(5,1-c)-1,2,4-triazoles and pyrazole derivatives FUJI PHOTO FILM CO., LTD. (JP) 1992-05-05 US disclosed
EP-0467327-A1 Silver halide color photographic photosensitive material and method of processing same FUJI PHOTO FILM CO., LTD. (JP) 1992-01-22 EP disclosed
EP-0457723-A2 Method for the stabilization of magenta couplers and the resulting dye-images in photographic materials CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0427225-A1 Direct positive color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354599-A1 INK SET AND INKJET RECORDING METHOD SETDB1, NAP1L1, NOM1 HDAC8 3018/4885HDAC6 2515/4885RAB9A 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.