SCHEMBL5490736

SCHEMBL5490736

O=CC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.47
LGALS3 P17931 2/20 0.47
LGALS9 O00182 1/20 0.47
LGALS8 O00214 1/20 0.47
CA12 O43570 5/20 0.42
CA1 P00915 5/20 0.42
CA2 P00918 5/20 0.42
CA9 Q16790 5/20 0.42
PYGB P11216 6/20 0.41
GAA P10253 1/20 0.41
CA4 P22748 2/20 0.40
CA5A P35218 2/20 0.40
CA7 P43166 2/20 0.40
CA3 P07451 1/20 0.40
CA13 Q8N1Q1 1/20 0.40
CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1035317 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL15382611 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL17993201 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL22902769 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL29055419 1.00 LGALS1 (0.47) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL15011450 0.98 LGALS1 (0.43) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL301532 0.98 LGALS1 (0.43) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL7155776 0.98 LGALS1 (0.43) LGALS1LGALS3LGALS9LGALS8CA12
SCHEMBL7151021 0.98 LGALS1 (0.43) LGALS1LGALS3LGALS9LGALS8CA12
Water SCHEMBL29046820 0.96 LGALS1 (0.42) LGALS1LGALS3LGALS9LGALS8CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 US disclosed
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 US disclosed
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein SANOFI (FR) 2021-08-17 US disclosed
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2019-07-11 US disclosed
WO-2019115616-A1 NOVEL 1,7-DICARBA-CLOSO-DODECABORANE(12) (META-CARBABORANE)-DERIVED CARBOXYLIC ACIDS SUITABLE FOR PEPTIDE MODIFICATION FOR APPLICATION IN BORON NEUTRON CAPTURE THERAPY (BNCT) UNIVERSITÄT LEIPZIG (DE) 2019-06-20 WO disclosed
EP-3463480-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2019-04-10 EP disclosed
EP-1551228-B1 SYNTHETIC C-GLYCOLIPID AND ITS USE FOR TREATING CANCER INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES UNIV NEW YORK (US) 2012-10-03 EP disclosed
US-8252909-B2 Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases NEW YORK UNIVERSITY (US) 2012-08-28 US disclosed
US-7273852-B2 Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2007-09-25 US disclosed
US-20060019246-A1 Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases NEW YORK UNIVERSITY (US) 2006-01-26 US disclosed
EP-1551228-A2 SYNTHETIC C-GLYCOLIPID AND ITS USE FOR TREATING CANCER INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES New York University (US) 2005-07-13 EP disclosed
EP-1543019-A2 MODIFIED PNA MOLECULES Santaris Pharma A/S (DK) 2005-06-22 EP disclosed
US-20040127429-A1 Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK, THE 2004-07-01 US disclosed
WO-2004024757-A2 MODIFIED PNA MOLECULES SANTARIS PHARMA A/S (DK) 2004-03-25 WO disclosed
WO-2003105769-A2 SYNTHETIC C-GLYCOLIPID AND ITS USE FOR TREATING CANCER INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES NEW YORK UNIVERSITY (US) 2003-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein GPR119, SLC2A8, SLC2A4 LGALS1 60/4885LGALS3 210/4885LGALS9 162/4885
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS1 60/4885LGALS3 210/4885LGALS9 162/4885
US-20040127429-A1 Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases UGT8, UGCG, SGMS1 LGALS1 495/4885LGALS3 786/4885LGALS9 835/4885
US-20060019246-A1 Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases CCR8, UGT8, H1-10 LGALS1 1140/4885LGALS3 1288/4885LGALS9 1217/4885
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS1 60/4885LGALS3 210/4885LGALS9 162/4885
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS1 60/4885LGALS3 210/4885LGALS9 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.