Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12880582 | 0.97 | TSHR (0.52) | CHRNB2CHRNA4TSHRACP3CYP1A2 | |
| SCHEMBL11820501 | 0.89 | TSHR (0.61) | CHRNB2CHRNA4TSHRALDH1A1MAPK1 | |
| SCHEMBL6075877 | 0.88 | CYP1A2 (0.68) | CHRNB2CHRNA4TSHRCYP1A2ALDH1A1 | |
| SCHEMBL11643928 | 0.86 | ALDH1A1 (0.65) | CHRNB2CHRNA4TSHRACP3CYP1A2 | |
| SCHEMBL151375 | 0.86 | TSHR (0.65) | TSHRALDH1A1MAPK1TAAR1HPGD | |
| SCHEMBL11642692 | 0.84 | CYP1A2 (0.45) | CHRNB2CHRNA4TSHRACP3CYP1A2 | |
| Water SCHEMBL28167159 | 0.83 | TSHR (0.61) | TSHRALDH1A1MAPK1TAAR1HPGD | |
| Hydrogen Sulfide SCHEMBL21379318 | 0.83 | TSHR (0.61) | TSHRALDH1A1MAPK1TAAR1HPGD | |
| Bromide SCHEMBL21831069 | 0.83 | TSHR (0.61) | TSHRALDH1A1MAPK1TAAR1HPGD | |
| SCHEMBL680180 | 0.81 | TSHR (0.68) | CHRNB2CHRNA4TSHRACP3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102399-B | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-116874429-A | Preparation method of medicinal bifonazole | 山东创新药物研发有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116023209-A | Synthesis method of intermediate and process for preparing bifonazole | 重庆西南制药二厂有限责任公司 | 2023-04-28 | — | — | CN | claimed |
| CN-112724142-A | Antidepressant theophylline derivative and preparation method thereof | 籍建亚 | 2021-04-30 | — | — | CN | claimed |
| CN-116102399-B | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-116874429-A | Preparation method of medicinal bifonazole | 山东创新药物研发有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116102399-A | Preparation method of biphenyl benzoxazole intermediate 4- (alpha-chlorobenzyl) biphenyl | 山东创新药物研发有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116023209-A | Synthesis method of intermediate and process for preparing bifonazole | 重庆西南制药二厂有限责任公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112724142-A | Antidepressant theophylline derivative and preparation method thereof | 籍建亚 | 2021-04-30 | — | — | CN | disclosed |
| CN-1110478-C | Biocidal benzylbiphenyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2003-06-04 | — | — | CN | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |
| CN-1295562-A | Biocidal benzylbiphenyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2001-05-16 | — | — | CN | disclosed |
| EP-1066259-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051578-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-14 | — | — | WO | disclosed |
| US-4243670-A | MICROBORICIDES; FUNGICIDES; SPORICIDES; HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| EP-0000017-A1 | 1-(2-Phenylethyl)-triazolium salts, their preparation and their use as fungicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |
| US-4118487-A | ANTIMICROBIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |