SCHEMBL680180

SCHEMBL680180

ClC(Cl)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 1/20 0.50
CHRNB2 P17787 1/20 0.50
CHRNA4 P43681 1/20 0.50
ACP3 P15309 2/20 0.46
PTGS2 P35354 1/20 0.46
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ESR2 Q92731 1/20 0.43
CYP17A1 P05093 1/20 0.39
ABCC4 O15439 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL23358393 0.92 TSHR (0.82) TSHRALDH1A1CYP1A2CHRNB2CHRNA4
SCHEMBL28353 0.82
SCHEMBL5490889 0.81 CHRNB2 (0.54) TSHRALDH1A1CYP1A2CHRNB2CHRNA4
Fluoride SCHEMBL28951268 0.79 TSHR (0.93) TSHRMAPK1TAAR1LMNA
Hydrochloric Acid SCHEMBL28478207 0.79 TSHR (0.93) TSHRALDH1A1CYP3A4MAPK1TAAR1
SCHEMBL27797843 0.79 TSHR (0.93) TSHRMAPK1TAAR1LMNA
SCHEMBL30292633 0.79 TSHR (0.93) TSHRMAPK1TAAR1LMNA
Water SCHEMBL11889376 0.79 TSHR (0.93) TSHRMAPK1TAAR1LMNA
SCHEMBL7032625 0.79 TSHR (0.93) TSHRMAPK1TAAR1LMNA
Hydrochloric Acid SCHEMBL27973361 0.79 TSHR (0.93) TSHRALDH1A1CYP3A4MAPK1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121583932-A Current collector for non-negative electrode lithium metal battery, and preparation method and application thereof 蜂巢能源科技股份有限公司 2026-02-27 CN claimed
CN-118416947-A High-selectivity ionic polymer catalytic material and preparation and application thereof 福州大学 2024-08-02 CN claimed
CN-221286924-U 4, 4-Dichloromethyl biphenyl production is with analytic tower 元氏天宇化工有限公司 2024-07-09 CN claimed
CN-118268030-A Solid sulfonic acid catalyst and preparation method and application thereof 华东理工大学 2024-07-02 CN claimed
CN-221259563-U Spiral condenser for producing 4, 4-dichloro methyl diphenyl 辛集市诚宇化工有限公司 2024-07-02 CN claimed
CN-115572371-B Preparation method of ionic porous polymer material and application of essential oil in adsorption and diterpene removal 杭州师范大学 2024-06-25 CN claimed
CN-220781562-U A rinsing cauldron for producing 4, 4-dichloro methyl biphenyl 辛集市诚宇化工有限公司 2024-04-16 CN claimed
CN-117777411-A Crosslinked methylene aromatic hydrocarbon high polymer and synthesis method thereof 乐山师范学院 2024-03-29 CN claimed
CN-117181990-B High-temperature-resistant precoated sand and preparation method thereof 胜利油田金岛实业有限责任公司 2024-03-19 CN claimed
CN-220573751-U Scraper centrifuge is used in production of 4, 4-dichloro methyl biphenyl 元氏天宇化工有限公司 2024-03-12 CN claimed
CN-101607871-B Method for preparing 4,4' -dimethylolbiphenyl SHANGHAI BAOSTEEL CHEMICAL CO 2012-07-11 CN claimed
CN-101973855-A Novel 4,4'-di(alkoxy/aryloxy methyl) biphenyl and preparation thereof SHANGHAI ECUST BIOMEDICINE CO LTD 2011-02-16 CN claimed
CN-101928198-A A preparation method of high-purity 4,4'-dichloromethyl biphenyl SHANGHAI ECUST BIOMEDICINE CO LTD 2010-12-29 CN claimed
CN-101607871-A Method for preparing 4, 4' -dimethylolbiphenyl SHANGHAI BAOSTEEL CHEMICAL CO (CN) 2009-12-23 CN claimed
EP-0840781-B1 METHODS AND DEVICES FOR THE REMOVAL OF PSORALENS FROM BLOOD PRODUCTS CERUS CORP (US) 2009-12-09 EP claimed
US-20080171814-A1 Polymer HALL RICHARD H 2008-07-17 US claimed
EP-1508345-A1 Absorbents and devices for the reduction of small organic compounds from blood products Cerus Corporation (US) 2005-02-23 EP claimed
US-5710187-A AROMATIC POLYMERS REACTED WITH HALOGEN CONTAINING COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-01-20 US claimed
US-5629353-A SEPARATION MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-05-13 US claimed
US-4448935-A CHLORO, BROMO OR HYDROXY AROMATIC CROSSLINKING AGENTS NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1984-05-15 US claimed