Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026023 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4ELMNACA2 | |
| SCHEMBL3256541 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNACA2 | |
| SCHEMBL9078886 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ELMNACA2 | |
| SCHEMBL8763537 | 0.82 | USP2 (0.42) | ALDH1A1MAPTLMNACA2SMN1; SMN2 | |
| Cyanate SCHEMBL7108613 | 0.76 | P4HB (0.42) | ALDH1A1MAPTKDM4ELMNACA2 | |
| SCHEMBL6624088 | 0.74 | IDO1 (0.52) | ALDH1A1MAPTKDM4EALOX15HPGD | |
| SCHEMBL3307820 | 0.73 | USP2 (0.37) | ALDH1A1MAPTLMNACA2SMN1; SMN2 | |
| SCHEMBL9751834 | 0.73 | USP2 (0.37) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8464396 | 0.72 | — | — | |
| SCHEMBL25142154 | 0.71 | MYC (0.40) | ALDH1A1MAPTLMNACA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033044-B | A kind of preparation method of pair of trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2019-02-12 | — | — | CN | claimed |
| CN-107033044-A | A kind of preparation method to trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2017-08-11 | — | — | CN | claimed |
| JP-4145006-A | — | — | None | — | — | JP | disclosed |
| CN-107033044-B | A kind of preparation method of pair of trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-107033044-B | A kind of preparation method of pair of trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-107033044-A | A kind of preparation method to trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-107033044-A | A kind of preparation method to trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-1997619-B | Ethynyl containing phenyl derivatives | HOFFMANN LA ROCHE | 2010-08-25 | — | — | CN | disclosed |
| US-7253192-B2 | Phenyl derivatives comprising an acetylene group | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |
| CN-1997619-A | Phenyl derivatives comprising an acetylene group | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | CN | disclosed |
| EP-1765760-A1 | PHENYL DERIVATIVES COMPRISING AN ACETYLENE GROUP | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-28 | — | — | EP | disclosed |
| EP-1205497-A2 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1138657-A1 | Process for generating electrophiles from anions by reaction with electrophilic fluorinating agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6270843-B1 | REACTING A SALT COMPRISING ANIONIC FORM OF SUBSTITUENT WITH AN ELECTROPHILIC FLUORINATION AGENT TO PROVIDE AN ELECTROPHILE COMPRISING CATIONIC FORM OF SUBSTITUENT; ELECTROPHILICALLY SUBSTITUTING ELECTROPHILE ON SUBSTRATE | AIR PRODUCTS AND CHEMICALS, INC. | 2001-08-07 | — | — | US | disclosed |
| JP-H04145006-A | INSECT-PROOFING AGENT COMPOSED MAINLY OF AROMATIC THIOCYANIC ACID COMPOUND AND SUITABLE FOR CORRUGATED FIBERBOARD, PAPER AND PAPER PRODUCT | RENGO CO LTD | 1992-05-19 | — | — | JP | disclosed |
| EP-0043736-B1 | PROPANOLAMINE DERIVATIVES, THEIR SALTS, PROCESSES FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1984-04-25 | — | — | EP | disclosed |
| US-4410548-A | HYPOTENSIVE AGENTS | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1983-10-18 | — | — | US | disclosed |
| EP-0043736-A1 | Propanolamine derivatives, their salts, processes for preparation and pharmaceutical compositions | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1982-01-13 | — | — | EP | disclosed |
| US-4018807-A | Synthesis of aromatic sulfur-oxygen transition metal complexes | AMERICAN CYANAMID COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-3959487-A | Control of mites with polychloro parathio phenols | PPG INDUSTRIES, INC. (US) | 1976-05-25 | — | — | US | disclosed |