SCHEMBL5491145

SCHEMBL5491145

CC(=O)SOS(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5133951 0.67
SCHEMBL20549181 0.67
SCHEMBL25244762 0.65
SCHEMBL3502969 0.65 CA2 (0.44)
SCHEMBL24394705 0.65
SCHEMBL27501424 0.65
SCHEMBL11169173 0.63
Acetone SCHEMBL27777446 0.63 LMNA (0.43)
Acetone SCHEMBL6749123 0.63 LMNA (0.43)
SCHEMBL28495896 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1038880-B1 Androstanes and pregnanes for allosteric modulation of GABA receptor EURO CELTIQUE SA (LU) 2007-10-17 EP claimed
US-6143736-A USED TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PREMENSTRUAL SYNDROME(PMS) AND POSTNATAL DEPRESSION (PND AND TO INDUCE ANESTHESIA COCENSYS, INC. (US) 2000-11-07 US claimed
EP-1038880-A2 Androstanes and pregnanes for allosteric modulation of GABA receptor COCENSYS, INC. (US) 2000-09-27 EP claimed
EP-0752860-A4 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS INC (US) 1998-05-06 EP claimed
EP-0752860-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1997-01-15 EP claimed
WO-1995021617-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1995-08-17 WO claimed
EP-1038880-B1 Androstanes and pregnanes for allosteric modulation of GABA receptor EURO CELTIQUE SA (LU) 2007-10-17 EP disclosed
US-6277838-B1 ADMINISTERING DOSAGE OF ANXIOLYTIC AGENT TO ANIMAL COCENSYS, INC. 2001-08-21 US disclosed
US-6143736-A USED TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PREMENSTRUAL SYNDROME(PMS) AND POSTNATAL DEPRESSION (PND AND TO INDUCE ANESTHESIA COCENSYS, INC. (US) 2000-11-07 US disclosed
EP-1038880-A2 Androstanes and pregnanes for allosteric modulation of GABA receptor COCENSYS, INC. (US) 2000-09-27 EP disclosed
US-5939545-A MODULATING THE GABA.SUB.A (GAMMA-AMINOBUTYRIC ACID A) RECEPTOR-CHLORIDE IONOPHORE COMPLEX TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PMS (PREMENSTRUAL SYNDROME) AND PND (POSTNATAL DEPRESSION) AND TO INDUCE ANESTHESIA COCENSYS, INC. (US) 1999-08-17 US disclosed
EP-0752860-A4 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS INC (US) 1998-05-06 EP disclosed
WO-1998005337-A1 USE OF GABA AND NMDA RECEPTOR LIGANDS FOR THE TREATMENT OF MIGRAINE HEADACHE COCENSYS, INC. (US) 1998-02-12 WO disclosed
EP-0752860-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1997-01-15 EP disclosed
WO-1995021617-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1995-08-17 WO disclosed