Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | CCKBR | P32239 | 3/20 | 0.45 |
| ▸ | CCKAR | P32238 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023555 | 0.97 | MAPT (0.51) | PSMB8PSMB9PSMB5MAPTPOLB | |
| SCHEMBL22343065 | 0.88 | MAPT (0.53) | PSMB8PSMB9PSMB5MAPTPOLB | |
| SCHEMBL28897027 | 0.87 | MAPT (0.54) | MAPTPOLBMAPK1PAX8TDP1 | |
| SCHEMBL30266615 | 0.87 | MAPT (0.54) | MAPTPOLBMAPK1PAX8TDP1 | |
| SCHEMBL28436040 | 0.87 | MAPT (0.54) | MAPTPOLBMAPK1PAX8TDP1 | |
| SCHEMBL30266675 | 0.87 | MAPT (0.54) | MAPTPOLBMAPK1PAX8TDP1 | |
| SCHEMBL28431835 | 0.87 | MAPT (0.55) | MAPTPOLBMAPK1PAX8TDP1 | |
| SCHEMBL28431032 | 0.87 | MAPT (0.55) | MAPTPOLBMAPK1PAX8TDP1 | |
| SCHEMBL1755615 | 0.86 | TDP1 (0.61) | MAPTPOLBPAX8TDP1KLK7 | |
| SCHEMBL17254256 | 0.85 | TDP1 (0.56) | MAPTPAX8TDP1KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163921-B1 | Peptide derivatives and medicinal compositions | NIPPON SHINYAKU CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1275657-A1 | PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |