Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755615 | 0.95 | TDP1 (0.61) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL20669110 | 0.94 | NPY4R (0.53) | TDP1PAX8MEN1KMT2ANPSR1 | |
| SCHEMBL28269289 | 0.94 | NPY4R (0.53) | TDP1PAX8MEN1KMT2ANPSR1 | |
| SCHEMBL12214996 | 0.92 | PAX8 (0.56) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL17254230 | 0.92 | PAX8 (0.53) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL17232586 | 0.92 | PAX8 (0.53) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL17553458 | 0.91 | PAX8 (0.52) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL12214999 | 0.90 | MMP1 (0.54) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL28269232 | 0.88 | PAX8 (0.46) | TDP1PAX8MAPTMEN1KMT2A | |
| SCHEMBL28269233 | 0.88 | PAX8 (0.46) | TDP1PAX8MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| US-20170173168-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| US-20170143845-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20150322155-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | Sushou M-conj Biotech Co., Ltd (CN) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | TDP1 4027/4885PAX8 3099/4885MAPT 4288/4885 |
| US-20170173168-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | TDP1 4027/4885PAX8 3099/4885MAPT 4288/4885 |
| US-20170143845-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | TDP1 4027/4885PAX8 3099/4885MAPT 4288/4885 |
| US-20150322155-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | DCLRE1A, AADAC, UACA | TDP1 3005/4885PAX8 2585/4885MAPT 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.