SCHEMBL5492278

SCHEMBL5492278

[C-]#[N+]c1ccc(C#Cc2c[c]ccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.33
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2188836 0.78 APP (0.57) APPMAPT
SCHEMBL5496752 0.77 TSHR (0.46) APPMAPT
SCHEMBL28019240 0.76 APP (0.37) APPMAPT
SCHEMBL5495027 0.76 APP (0.47) APPMAPT
SCHEMBL4268626 0.76 APP (0.37) APPMAPT
SCHEMBL2545694 0.76 APP (0.37) APPMAPT
SCHEMBL5492434 0.76 MAPT (0.59) APPMAPT
SCHEMBL2539548 0.76 APP (0.37) APPMAPT
SCHEMBL10300064 0.72 CA2 (0.41) APP
SCHEMBL5490248 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474832-A4 METHOD AND SYSTEM FOR MOLECULAR CHARGE STORAGE FIELD EFFECT TRANSISTOR UNIV CALIFORNIA (US) 2007-08-29 EP disclosed
US-20050062097-A1 Method and system for molecular charge storage field effect transistor REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2005-03-24 US disclosed
EP-1474832-A1 METHOD AND SYSTEM FOR MOLECULAR CHARGE STORAGE FIELD EFFECT TRANSISTOR The Regents of the University of California (US) 2004-11-10 EP disclosed
US-6674121-B2 Method and system for molecular charge storage field effect transistor THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-06 US disclosed
WO-2003052835-A1 METHOD AND SYSTEM FOR MOLECULAR CHARGE STORAGE FIELD EFFECT TRANSISTOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-06-26 WO disclosed
US-20030111670-A1 Method and system for molecular charge storage field effect transistor THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-06-19 US disclosed