Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435480 | 1.00 | SCN9A (0.30) | SCN9A | |
| SCHEMBL436183 | 0.79 | CYP3A4 (0.34) | SCN9A | |
| SCHEMBL4614199 | 0.79 | SCN9A (0.35) | SCN9A | |
| SCHEMBL16046506 | 0.69 | CHRNB2 (0.38) | SCN9A | |
| SCHEMBL22321085 | 0.68 | MEN1 (0.41) | SCN9A | |
| SCHEMBL27199191 | 0.68 | CNR1 (0.37) | SCN9A | |
| SCHEMBL5492318 | 0.68 | MEN1 (0.41) | — | |
| SCHEMBL435479 | 0.68 | MEN1 (0.41) | — | |
| SCHEMBL7167055 | 0.67 | TAAR1 (0.32) | — | |
| SCHEMBL8795608 | 0.67 | SCN9A (0.36) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773816-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006002421-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-01-05 | — | — | WO | disclosed |