Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9636228 | 0.91 | CHRM5 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL758122 | 0.84 | CHRM5 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Bromide SCHEMBL366431 | 0.82 | GALR3 (0.45) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL366719 | 0.82 | CHRM5 (0.45) | POLBCHRM5CHRM1CHRM3CHRM2 | |
| Iodide SCHEMBL10787028 | 0.82 | CHRM5 (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL1262968 | 0.79 | LMNA (0.40) | TBXA2RGAACYP2C19LMNATSHR | |
| SCHEMBL6544577 | 0.78 | SLC22A16 (0.33) | POLBMAPT | |
| SCHEMBL18690273 | 0.76 | ACHE (0.44) | POLBCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL34072 | 0.75 | CHRM5 (0.50) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL1292784 | 0.75 | CHRM5 (0.50) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398019-A1 | Direct electroplating of through-holes | International Business Machines Corporation (US) | 1990-11-22 | — | — | EP | claimed |
| US-7186674-B2 | Topical cleansing composition | L'OREAL (FR) | 2007-03-06 | — | — | US | disclosed |
| WO-2005040253-A1 | METHOD FOR PREPARING A LATEX WITH A MODIFIED SURFACE CHEMISTRY, THE LATEX OBTAINABLE BY SAID METHOD AND THE USES THEREOF IN CONSTRUCTION | RHODIA CHIMIE (FR) | 2005-05-06 | — | — | WO | disclosed |
| US-20030209799-A1 | Copper plated PTH barrels and methods for fabricating | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-11-13 | — | — | US | disclosed |
| US-6630743-B2 | Copper plated PTH barrels and methods for fabricating | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-10-07 | — | — | US | disclosed |
| US-20020195716-A1 | Copper plated PTH barrels and methods for fabricating | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2002-12-26 | — | — | US | disclosed |
| US-20020037267-A1 | Topical cleansing composition | L'OREAL (FR) | 2002-03-28 | — | — | US | disclosed |
| US-6265075-B1 | Circuitized semiconductor structure and method for producing such | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-07-24 | — | — | US | disclosed |
| US-5509557-A | Depositing a conductive metal onto a substrate | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0664664-A1 | Depositing a conductive metal onto a substrate | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-07-26 | — | — | EP | disclosed |
| EP-0144612-B1 | METHOD FOR SELECTIVE ELECTROLESS PLATING COPPER ONTO A NON-CONDUCTIVE SUBSTRATE SURFACE | International Business Machines Corporation (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0233475-A2 | Method of particulating agglomerated catalyst materials | PHILLIPS PETROLEUM COMPANY (US) | 1987-08-26 | — | — | EP | disclosed |
| US-4681266-A | REFRACTORY FINES, BEATER MILLING | PHILLIPS PETROLEUM COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| US-4659690-A | REDUCING FINES IN CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0188658-A2 | Acid agglomeration of refractory gel in polar organic diluent | PHILLIPS PETROLEUM COMPANY (US) | 1986-07-30 | — | — | EP | disclosed |
| US-4535070-A | Acrylamide polymer used to reduce fines in aluminum phosphate gel | PHILLIPS PETROLEUM COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| US-4534768-A | Sealant pad for external catheter and method of use thereof | HOLLISTER INCORPORATED (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0144612-A2 | Method for selective electroless plating copper onto a non-conductive substrate surface | International Business Machines Corporation (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4477325-A | Skin barrier composition comprising an irradiated crosslinked ethylene-vinyl acetate copolymer and polyisobutylene | HOLLISTER INCORPORATED (US) | 1984-10-16 | — | — | US | disclosed |
| US-4448804-A | ACTIVATION WITH STANNOUS CHLORIDE-PALLADIUM CHLORIDE PARTICLES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |