Butyrolactone

Butyrolactone

SCHEMBL5492647

CCCCOCCOCCCC.O=C1CCCO1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.47
CA9 Q16790 1/20 0.47
CYP1A2 P05177 3/20 0.41
TSHR P16473 4/20 0.40
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RARB P10826 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyrolactone SCHEMBL2671380 0.88 ALDH1A1 (0.46) CA1CA9CYP1A2TSHRCYP3A4
Butyrolactone SCHEMBL28205035 0.87 CA1 (0.52) CA1CA9CYP1A2TSHRALDH1A1
SCHEMBL28812396 0.86 CA1 (0.53) CA1CA9CYP1A2ALDH1A1MEN1
SCHEMBL27960286 0.86 CA1 (0.53) CA1CA9CYP1A2ALDH1A1MEN1
SCHEMBL28068299 0.86 CA1 (0.53) CA1CA9CYP1A2ALDH1A1MEN1
SCHEMBL27996483 0.86 CA1 (0.53) CA1CA9CYP1A2ALDH1A1MEN1
Butyrolactone SCHEMBL28649882 0.85 CA1 (0.50) CA1CA9TSHRALDH1A1LMNA
Butyrolactone SCHEMBL9507414 0.80 CA1 (0.64) CA1CA9CYP1A2TSHRALDH1A1
Acetic Acid Butyl Ester SCHEMBL9131200 0.80 ALDH1A1 (0.56) CA1CA9TSHRALDH1A1SMN1; SMN2
Acetic Acid Butyl Ester SCHEMBL9131190 0.80 ALDH1A1 (0.56) CA1CA9TSHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070207389-A1 Non-aqueous electrolyte and lithium secondary battery using the same UBE INDUSTRIES, LTD. 2007-09-06 US claimed
US-20040121240-A1 Non-aqueous electrolyte and lithium secondary battery using the same UBE INDUSTRIES, LTD. 2004-06-24 US claimed
US-20030148190-A1 Non-aqueous electrolyte and lithium secondary battery using the same UBE INDUSTRIES, LTD. (JP) 2003-08-07 US claimed
US-6479191-B1 COMPRISING A NON-AQUEOUS SOLVENT, AN ELECTROLYTE SALT DISSOLVED THEREIN AND AT LEAST ONE ALKYNE DERIVATIVE UBE INDUSTRIES, LTD. (JP) 2002-11-12 US claimed
US-6436582-B1 A NON-AQUEOUS SOLVENT AND (II) AN ELECTROLYTE SALT DISSOLVED THEREIN AND (III) A DISULFONATE ESTER DERIVATIVE UBE INDUSTRIES, LTD. (JP) 2002-08-20 US claimed