SCHEMBL5492803

SCHEMBL5492803

O=[C]CSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.50
DNMT1 P26358 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1526443 0.79 KIF11 (0.57) KIF11
SCHEMBL5580308 0.71 KIF11 (0.64) KIF11
SCHEMBL974721 0.71 KIF11 (0.63) KIF11
SCHEMBL5545280 0.70 KIF11 (0.56) KIF11
SCHEMBL6130697 0.70 KIF11 (0.56) KIF11
Ethyl(Trityl)Sulfane SCHEMBL4755270 0.70 KIF11 (0.56) KIF11
SCHEMBL12846954 0.70 KIF11 (0.51) KIF11DNMT1
SCHEMBL342181 0.70 KIF11 (0.50) KIF11DNMT1
SCHEMBL2303040 0.70 KIF11 (0.51) KIF11DNMT1
SCHEMBL1706141 0.70 KIF11 (0.50) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975374-B1 RADIOMETAL-BINDING PEPTIDE ANALOGUES IMMUNOMEDICS INC (US) 2007-12-05 EP disclosed
US-7045503-B1 Radiometal-binding peptide analogues IMMUNOMEDICS, INC. (US) 2006-05-16 US disclosed
EP-0975374-A4 RADIOMETAL-BINDING PEPTIDE ANALOGUES IMMUNOMEDICS INC (US) 2004-05-26 EP disclosed
US-20030207400-A1 Vectors for dna delivery BIANCHI ELISABETTA (IT) 2003-11-06 US disclosed
EP-0975374-A1 RADIOMETAL-BINDING PEPTIDE ANALOGUES Immunomedics, Inc. (US) 2000-02-02 EP disclosed
US-5753206-A Radiometal-binding analogues of luteinizing hormone releasing hormone IMMUNOMEDICS, INC. (US) 1998-05-19 US disclosed
WO-1998002192-A1 RADIOMETAL-BINDING PEPTIDE ANALOGUES IMMUNOMEDICS, INC. (US) 1998-01-22 WO disclosed