SCHEMBL5545280

SCHEMBL5545280

[CH2]CSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248982 0.81 KIF11 (0.63) KIF11
SCHEMBL14944742 0.78 KIF11 (0.48) KIF11
SCHEMBL19661459 0.76 KIF11 (0.52) KIF11
SCHEMBL8054796 0.76 KIF11 (0.49) KIF11
Ethyl(Trityl)Sulfane SCHEMBL4755270 0.75 KIF11 (0.56) KIF11
SCHEMBL6130697 0.75 KIF11 (0.56) KIF11
SCHEMBL1648406 0.75 KIF11 (0.50) KIF11
SCHEMBL1533885 0.74 KIF11 (0.55) KIF11
SCHEMBL7796199 0.74 KIF11 (0.55) KIF11
Benzyl(Trityl)Sulfane SCHEMBL7543647 0.73 KIF11 (0.54) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119567-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2022-04-21 US claimed
US-20170204102-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT THE REPUBLIC OF KOREA (MANAGEMENT: RURAL DEVELOPMENT ADMINISTRATION) (KR) 2017-07-20 US claimed
US-20150119251-A1 AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT REPUBLIC OF KOREA (RURAL DEVELOPMENT ADMINISTRATION) (KR) 2015-04-30 US claimed
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Kongju National University Industry- University Cooperation Foundation (KR) 2013-07-25 US claimed
EP-2594134-A2 AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Republic of Korea (Management: Rural Development Administration) (KR) 2013-05-22 EP claimed
EP-4341270-A1 CHEMICAL PHOSPHORYLATION REAGENTS, PREPARATION, AND THEIR USES Olix US, Inc. (US) 2024-03-27 EP disclosed
CN-117580848-A Chemical phosphorylating reagent, preparation and use thereof 奥利克斯美国公司 2024-02-20 CN disclosed
US-20230233700-A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES GENENTECH, INC. (US) 2023-07-27 US disclosed
CN-116406368-A Conjugated compounds derived from sibs and methods of use thereof 赖利制药公司 2023-07-07 CN disclosed
US-11619880-B2 Holographic photopolymer compositions and composites THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2023-04-04 US disclosed
US-11547762-B2 Methods for preparing antibody drug conjugates GENENTECH, INC. (US) 2023-01-10 US disclosed
US-20220119567-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2022-04-21 US disclosed
US-20150119251-A1 AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT REPUBLIC OF KOREA (RURAL DEVELOPMENT ADMINISTRATION) (KR) 2015-04-30 US disclosed
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Kongju National University Industry- University Cooperation Foundation (KR) 2013-07-25 US disclosed
EP-2594134-A2 AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Republic of Korea (Management: Rural Development Administration) (KR) 2013-05-22 EP disclosed
US-7276598-B2 Phosphorylation reagents for improved processes to convert terminal hydroxyl groups of oligonucleotides into phosphate monoesters SIGMA-ALDRICH CO. (US) 2007-10-02 US disclosed
US-20040230047-A1 Coupling phosphoramidites; phosphates removable in one deprotection step; solid phase synthesis PROLIGO, LLC (US) 2004-11-18 US disclosed
EP-0816368-B1 Chemical phoshorylation of oligonucleotides and reactants used therefor GLEN RES CORP (US) 2003-01-08 EP disclosed
US-5959090-A FORMING PHOSPHORAMIDITE COMPOUNDS FROM PHOSPHORYLATION GLEN RESEARCH CORPORATION (US) 1999-09-28 US disclosed
EP-0816368-A1 Chemical phoshorylation of oligonucleotides and reactants used therefor Glen Research Corporation (US) 1998-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204102-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT HDHD5, DAZAP1, MAPKAPK5 KIF11 1543/4885
US-20040230047-A1 Coupling phosphoramidites; phosphates removable in one deprotection step; solid phase synthesis DIMT1, RNGTT, ADAR KIF11 3057/4885
US-20230233700-A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES FCGRT, MSN, FCGR3B KIF11 678/4885
US-11547762-B2 Methods for preparing antibody drug conjugates FCGRT, MSN, FCGR3B KIF11 678/4885
US-20150119251-A1 AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT PEPD, DNPEP, DPP7 KIF11 4255/4885
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT HDHD5, DAZAP1, MAPKAPK5 KIF11 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.