Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 1.00 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 1.00 |
| ▸ | CETP | P11597 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.61 |
| ▸ | GMNN | O75496 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.61 |
| ▸ | CCR6 | P51684 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | UBE2N | P61088 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylspingosine SCHEMBL8258015 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CETPMEN1KMT2A | |
| Dimethylspingosine SCHEMBL121926 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CETPMEN1KMT2A | |
| Dimethylspingosine SCHEMBL121927 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CETPMEN1KMT2A | |
| Dimethylspingosine SCHEMBL19745875 | 0.93 | SPHK2 (0.86) | SPHK2SPHK1CETPMEN1KMT2A | |
| SCHEMBL14020662 | 0.85 | SPHK2 (0.74) | SPHK2SPHK1CETPMEN1KMT2A | |
| SCHEMBL8912325 | 0.85 | SPHK2 (0.74) | SPHK2SPHK1CETPMEN1KMT2A | |
| SCHEMBL21428462 | 0.84 | SPHK2 (0.72) | SPHK2SPHK1CETPMEN1KMT2A | |
| SCHEMBL29455695 | 0.83 | SPHK2 (0.70) | SPHK2SPHK1CETPMEN1KMT2A | |
| SCHEMBL11895494 | 0.79 | SPHK2 (0.69) | SPHK2SPHK1CETPMEN1KMT2A | |
| Sphingosine SCHEMBL27529594 | 0.79 | SPHK2 (0.90) | SPHK2SPHK1CETPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070077283-A1 | METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS | NASTECH PHARMACEUTICAL COMPANY INC. | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070077283-A1 | METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS | PGF, PLAT, PTAFR | SPHK2 270/4885SPHK1 367/4885CETP 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.