Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | LPL | P06858 | 2/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326914 | 1.00 | CYP1A2 (0.59) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| SCHEMBL28572624 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| SCHEMBL28182287 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| Hydrochloric Acid SCHEMBL7988640 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| Hydrogen Sulfide SCHEMBL28268146 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| SCHEMBL30057561 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| SCHEMBL6546987 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| SCHEMBL27348511 | 0.97 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| Hydrogen Peroxide SCHEMBL27723527 | 0.95 | CYP1A2 (0.54) | CYP1A2CYP2A6TAAR1LPLLIPG | |
| SCHEMBL6546453 | 0.92 | CYP1A2 (0.52) | CYP1A2CYP2A6TAAR1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202766-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-20070078080-A1 | N4-Acylcytosine Nucleosides for Treatment of Viral Infections | GILEAD PHARMASSET LLC | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078080-A1 | N4-Acylcytosine Nucleosides for Treatment of Viral Infections | ENTPD5, DUT, NT5C3B | CYP1A2 1240/4885CYP2A6 1327/4885TAAR1 3913/4885 |
| US-20120202766-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | ENTPD5, DUT, NT5C3B | CYP1A2 1174/4885CYP2A6 1296/4885TAAR1 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.