Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | NPY4R | P50391 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492163 | 0.89 | CCKBR (0.60) | CCKBRNPY1RNPY2RNPY4R | |
| SCHEMBL7027512 | 0.88 | HDAC3 (0.53) | CCKBRCTSLCTSSCTSK | |
| SCHEMBL5490038 | 0.87 | CCKBR (0.62) | CCKBRNPY1RNPY2RNPY4R | |
| SCHEMBL13608838 | 0.87 | CTSL (0.54) | CCKBRCTSLCTSSCTSK | |
| SCHEMBL5497574 | 0.84 | CCKBR (0.59) | CCKBRNPY1RNPY2RNPY4R | |
| SCHEMBL5489809 | 0.84 | CCKBR (0.55) | CCKBR | |
| SCHEMBL13620425 | 0.84 | CTSL (0.56) | CTSLCTSSCTSK | |
| SCHEMBL13702223 | 0.83 | CTSL (0.65) | CCKBRCTSLCTSSCTSK | |
| SCHEMBL30906925 | 0.83 | CTSL (0.65) | CCKBRCTSLCTSSCTSK | |
| SCHEMBL5497992 | 0.83 | CCKBR (0.61) | CCKBRNPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163921-B1 | Peptide derivatives and medicinal compositions | NIPPON SHINYAKU CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1275657-A1 | PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |