Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97249 | 0.83 | CYP1A2 (0.67) | CYP1A2CYP2D6NPSR1 | |
| Hydrochloric Acid SCHEMBL251768 | 0.82 | CYP1A2 (0.64) | CYP1A2CYP2D6NPSR1 | |
| SCHEMBL11592977 | 0.76 | NAAA (0.47) | CYP1A2CYP2D6 | |
| SCHEMBL8669987 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP2D6NPSR1 | |
| SCHEMBL11269557 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP2D6NPSR1 | |
| SCHEMBL408946 | 0.72 | NPSR1 (0.40) | CYP1A2CYP2D6NPSR1 | |
| SCHEMBL988586 | 0.72 | NAAA (0.52) | CYP1A2CYP2D6NPSR1 | |
| Hydrochloric Acid SCHEMBL4790313 | 0.71 | NPSR1 (0.39) | CYP1A2CYP2D6NPSR1 | |
| SCHEMBL28278980 | 0.71 | CYP1A2 (0.85) | CYP1A2CYP2D6 | |
| SCHEMBL7501948 | 0.70 | CYP1A2 (0.39) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002042415-A9 | AGENTS FOR BLOCKING T CELL MEDIATED IMMUNE REACTIONS | THE OHIO STATE UNIVERSITY (US) | 2011-12-29 | — | — | WO | disclosed |
| US-7220822-B2 | CD28 mimetics for blocking T cell mediated immune reactions | THE OHIO STATE UNIVERSITY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20020156008-A1 | Agents for blocking T cell mediated immune reactions | OHIO STATE INNOVATION FOUNDATION | 2002-10-24 | — | — | US | disclosed |
| WO-2002042415-A2 | AGENTS FOR BLOCKING T CELL MEDIATED IMMUNE REACTIONS | THE OHIO STATE UNIVERSITY (US) | 2002-05-30 | — | — | WO | disclosed |