SCHEMBL5494369

SCHEMBL5494369

O=C(OC(=O)C1NCCO1)C1NCCO1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27464952 0.85
SCHEMBL28084230 0.83
SCHEMBL6595404 0.79
SCHEMBL1053760 0.79
SCHEMBL7277964 0.78 ARG1 (0.33) ARG1
SCHEMBL3843714 0.78 USP2 (0.33)
SCHEMBL28794364 0.78
SCHEMBL28050533 0.78 CA4 (0.35)
SCHEMBL28016407 0.77 CA4 (0.34)
SCHEMBL5274452 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288665-B1 Process for selective derivatization of taxanes FLORIDA STATE UNIVERSITY (US) 2007-10-30 US claimed
EP-0956284-B1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES UNIV FLORIDA STATE (US) 2006-10-04 EP claimed
EP-1170293-B1 Process for selective derivatization of taxanes UNIV FLORIDA STATE (US) 2006-05-17 EP claimed
CN-1205196-C Process for selective derivatization of taxanes UNIV FLORIDA STATE (US) 2005-06-08 CN claimed
EP-1170293-A2 Process for selective derivatization of taxanes Florida State University (US) 2002-01-09 EP claimed
EP-0956284-A4 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES UNIV FLORIDA STATE (US) 2001-12-05 EP claimed
CN-1239476-A Process for selective derivatization of taxanes UNIV FLORIDA STATE (US) 1999-12-22 CN claimed
EP-0956284-A1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES Florida State University (US) 1999-11-17 EP claimed
WO-1999009021-A1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES FLORIDA STATE UNIVERSITY (US) 1999-02-25 WO claimed
US-7288665-B1 Process for selective derivatization of taxanes FLORIDA STATE UNIVERSITY (US) 2007-10-30 US disclosed
EP-1795528-A1 Process for selective derivatization of taxanes Florida State University (US) 2007-06-13 EP disclosed
EP-1170292-B1 Process for selective derivatization of taxanes UNIV FLORIDA STATE (US) 2007-04-25 EP disclosed
EP-0956284-B1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES UNIV FLORIDA STATE (US) 2006-10-04 EP disclosed
EP-1671960-A2 Process for selective derivatization of taxanes Florida State University (US) 2006-06-21 EP disclosed
EP-0956284-A4 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES UNIV FLORIDA STATE (US) 2001-12-05 EP disclosed
US-6291691-B1 CONVERTING THE C(7) HYDROXY GROUP OF A 10-ACYLOXY-9-OXO-7-HYDROXYTAXANE TO AN ACETAL OR KETAL, BY REACTING WITH KETALIZING AGENT IN PRESENCE OF AN ACID CATALYST TO FORM FLORIDA STATE UNIVERSITY 2001-09-18 US disclosed
US-6191287-B1 TREATING THE TAXANE WITH A SILYAMIDE OR A BISSILYLAMIDE TO FORM C10 SILYLATED TAXANE FLORIDA STATE UNIVERSITY 2001-02-20 US disclosed
CN-1239476-A Process for selective derivatization of taxanes UNIV FLORIDA STATE (US) 1999-12-22 CN disclosed
EP-0956284-A1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES Florida State University (US) 1999-11-17 EP disclosed
WO-1999009021-A1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES FLORIDA STATE UNIVERSITY (US) 1999-02-25 WO disclosed