Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818303 | 0.88 | USP2 (0.31) | USP2SMN1; SMN2MAPK1 | |
| SCHEMBL28084230 | 0.79 | — | — | |
| SCHEMBL5494369 | 0.78 | ARG1 (0.31) | — | |
| SCHEMBL2134991 | 0.75 | ARG1 (0.38) | MAPK1 | |
| SCHEMBL2135002 | 0.75 | ARG1 (0.38) | MAPK1 | |
| SCHEMBL2134995 | 0.75 | ARG1 (0.38) | MAPK1 | |
| SCHEMBL27435827 | 0.74 | ALDH1A1 (0.35) | MAPK1RECQL | |
| SCHEMBL27464952 | 0.73 | — | — | |
| SCHEMBL6595404 | 0.72 | — | — | |
| SCHEMBL20521203 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683257-B2 | Methods and intermediates for synthesizing SK1-I | ENZO BIOCHEM, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| US-20200131113-A1 | METHODS AND INTERMEDIATES FOR SYNTHESIZING SK1-I | ENZO BIOCHEM, INC. (US) | 2020-04-30 | — | — | US | disclosed |
| US-20190256453-A1 | METHODS AND INTERMEDIATES FOR SYNTHESIZING SK1-I | ENZO BIOCHEM, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-10364211-B1 | Methods and intermediates for synthesizing SK1-I | ENZO BIOCHEM, INC. (US) | 2019-07-30 | — | — | US | disclosed |
| CN-108602809-A | Inhibitors of isoxazolidine derived receptor interacting protein kinase 1(RIPK 1) | 戴纳立制药公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-2283150-B1 | ASSAY FOR MONITORING ACTIVITY OF JMJD6 | ISIS INNOVATION (GB) | 2013-01-02 | — | — | EP | disclosed |
| WO-2009141609-A1 | ASSAY FOR MONITORING ACTIVITY OF JMJD6 | ISIS INNOVATION LIMITED (GB) | 2009-11-26 | — | — | WO | disclosed |
| CN-1874991-A | Compounds capable of binding to the S1P receptor and pharmaceutical uses thereof | ONO PHARMACEUTICAL CO (JP) | 2006-12-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683257-B2 | Methods and intermediates for synthesizing SK1-I | SKP1, SKP2, KMT5A | USP2 3063/4885SMN1; SMN2 1584/4885MAPK1 247/4885 |
| US-20200131113-A1 | METHODS AND INTERMEDIATES FOR SYNTHESIZING SK1-I | SKP1, SKP2, KMT5A | USP2 3063/4885SMN1; SMN2 1584/4885MAPK1 247/4885 |
| US-20190256453-A1 | METHODS AND INTERMEDIATES FOR SYNTHESIZING SK1-I | SKP1, SKP2, KMT5A | USP2 3063/4885SMN1; SMN2 1584/4885MAPK1 247/4885 |
| US-10364211-B1 | Methods and intermediates for synthesizing SK1-I | SKP1, SKP2, KMT5A | USP2 3063/4885SMN1; SMN2 1584/4885MAPK1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.