Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 11/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501013 | 0.83 | HTR5A (0.36) | HTR5AMAPTGAAL3MBTL1HTR1A | |
| SCHEMBL28733042 | 0.77 | HTR2C (0.42) | HTR5AHTR1AHTR1DHTR2CHTR7 | |
| SCHEMBL11573586 | 0.77 | MAPT (0.39) | MAPTKDM4EGAAL3MBTL1HTR6 | |
| SCHEMBL13366003 | 0.75 | HTR5A (0.48) | HTR5AMAPTGAAHTR2CTSHR | |
| SCHEMBL31474673 | 0.75 | HTR5A (0.48) | HTR5AMAPTGAAHTR2CTSHR | |
| SCHEMBL5496349 | 0.73 | HTR5A (0.38) | HTR5AMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL3905870 | 0.70 | GRM2 (0.41) | MAPTKDM4EGAAL3MBTL1HTR2C | |
| SCHEMBL20777509 | 0.69 | KDM4E (0.41) | HTR5AMAPTKDM4EGAAHTR1A | |
| SCHEMBL5500090 | 0.67 | MAPT (0.40) | HTR5AMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL20385185 | 0.67 | HTR5A (0.48) | HTR5AMAPTGAAHTR2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765592-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics N.V. (BE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005688-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR. | AGFA-GEVAERT (BE) | 2006-01-19 | — | — | WO | disclosed |