Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 14/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494475 | 0.83 | HTR5A (0.36) | HTR5AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL27589412 | 0.81 | HTR5A (0.35) | HTR5ADDB1CRBNMEN1KMT2A | |
| SCHEMBL5502020 | 0.77 | HTR5A (0.37) | HTR5ADDB1CRBNHTR2AHTR2C | |
| SCHEMBL28733042 | 0.74 | HTR2C (0.42) | HTR5ADDB1CRBNMEN1KMT2A | |
| SCHEMBL5495275 | 0.73 | KMT2A (0.44) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL13366003 | 0.72 | HTR5A (0.48) | HTR5AMEN1KMT2AGAAMAPT | |
| SCHEMBL31474673 | 0.72 | HTR5A (0.48) | HTR5AMEN1KMT2AGAAMAPT | |
| SCHEMBL27706751 | 0.67 | HSD17B10 (0.41) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| Fluoride SCHEMBL4299936 | 0.66 | MEN1 (0.35) | DDB1CRBNMEN1KMT2AGAA | |
| SCHEMBL3897467 | 0.66 | ALDH1A1 (0.43) | DDB1CRBNMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765592-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics N.V. (BE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005688-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR. | AGFA-GEVAERT (BE) | 2006-01-19 | — | — | WO | disclosed |