Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 14/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494456 | 0.91 | XIAP (0.45) | XIAPELANEDPP4PREPFAP | |
| SCHEMBL29689606 | 0.80 | XIAP (0.53) | XIAPELANEDPP4PREPFAP | |
| SCHEMBL5493484 | 0.77 | NPSR1 (0.33) | — | |
| SCHEMBL5493485 | 0.77 | NPSR1 (0.33) | — | |
| SCHEMBL5496665 | 0.77 | ELANE (0.46) | XIAPELANEDPP4DPP8DPP9 | |
| SCHEMBL3843803 | 0.74 | POLB (0.47) | XIAPELANE | |
| SCHEMBL30563254 | 0.74 | ELANE (0.44) | XIAPELANEDPP4PREPFAP | |
| SCHEMBL22546193 | 0.74 | XIAP (0.49) | XIAPELANEDPP4PREPFAP | |
| SCHEMBL5489331 | 0.73 | DPP7 (0.41) | DPP4DPP8DPP9 | |
| SCHEMBL5489340 | 0.73 | DPP7 (0.41) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |