Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061754 | 0.88 | LMNA (0.62) | LMNACYP2C19KMT2ATSHRMEN1 | |
| (S)-Methylphenobarbital SCHEMBL35625 | 0.85 | LMNA (1.00) | LMNACYP2C19KMT2ATSHRMEN1 | |
| Mephobarbital SCHEMBL35624 | 0.85 | LMNA (1.00) | LMNACYP2C19KMT2ATSHRMEN1 | |
| (R)-Methylphenobarbital SCHEMBL11789851 | 0.85 | LMNA (1.00) | LMNACYP2C19KMT2ATSHRMEN1 | |
| SCHEMBL28077903 | 0.83 | LMNA (0.69) | LMNACYP2C19KMT2ATSHRMEN1 | |
| Mephobarbital SCHEMBL29694125 | 0.83 | LMNA (0.97) | LMNACYP2C19KMT2ATSHRMEN1 | |
| SCHEMBL27853847 | 0.83 | LMNA (0.69) | LMNACYP2C19KMT2ATSHRMEN1 | |
| SCHEMBL11530438 | 0.83 | LMNA (0.69) | LMNACYP2C19KMT2ATSHRMEN1 | |
| Mephobarbital SCHEMBL28475568 | 0.83 | LMNA (0.97) | LMNACYP2C19KMT2ATSHRMEN1 | |
| SCHEMBL17791220 | 0.81 | LMNA (0.66) | LMNACYP2C19KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070104696-A1 | Use of cell lines to produce active therapeutic proteins | MULTICELL TECHNOLOGIES, INC. (US) | 2007-05-10 | — | — | US | disclosed |