Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL143291 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL30589345 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL31315413 | 1.00 | — | — | |
| Choline SCHEMBL28050384 | 0.96 | — | — | |
| Choline SCHEMBL10779307 | 0.96 | CYP3A4 (0.93) | — | |
| Choline SCHEMBL27565807 | 0.96 | — | — | |
| Choline SCHEMBL1934626 | 0.96 | MEN1 (0.80) | — | |
| Choline SCHEMBL2678893 | 0.96 | — | — | |
| Choline SCHEMBL20490075 | 0.96 | MEN1 (0.80) | — | |
| Choline SCHEMBL396926 | 0.96 | MEN1 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 16305 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260150612-A1 | SURFACE CONDITIONING PROCESSES FOR SEMICONDUCTOR PROCESSING CHAMBER PARTS | APPLIED MATERIALS, INC (US) | 2026-05-28 | — | — | US | claimed |
| CN-122082124-A | Semiconductor surface treating agent and application thereof, and silicon carbide laser modified layer stripping method | — | 2026-05-26 | — | — | CN | claimed |
| CN-118908237-B | Super cage Na with high proportion+FAU molecular sieve for exchange position and application of FAU molecular sieve to adsorption separation of fluorine-containing electronic gas | JIANG University OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080783-A | Environment-friendly and efficient 4H-SiC polishing solution and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| WO-2026103552-A1 | CLEANING COMPOSITION | 安集微电子科技（上海）股份有限公司 | 2026-05-21 | — | — | WO | claimed |
| CN-122059887-A | CIS chip protection material low-damage remover and preparation method and application thereof | 浙江奥首材料科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-116270428-B | Glycyrrhetinic acid injectable hydrogel and preparation method and application thereof | 广西医科大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122037231-A | Method for preparing lignin with high hydroxyl content and low condensation degree by taking moso bamboo as raw material | 南京林业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122038058-A | Cleaning composition | 安集微电子科技（上海）股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037229-A | Method for extracting lignin | 安琪酵母股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-0099071-A2 | Process for the preparation of monobenzoylated 1,4-diaminoanthraquinones | BAYER AG (DE) | 1984-01-25 | — | — | EP | claimed |
| EP-0025926-B1 | PROCESS FOR THE PREPARATION OF MONOAROYLATED 1,4-DIAMINO ANTHRAQUINONES | BAYER AG (DE) | 1982-11-24 | — | — | EP | claimed |
| US-4339340-A | HYDROXYLAKYL/TRIALKYLAMMONIUM HYDROXIDE | TOKYO SHIBAURA ELECTRIC CO., LTD. (JP) | 1982-07-13 | — | — | US | claimed |
| US-4324879-A | Process for the preparation of polyisocyanates containing isocyanurate groups and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | claimed |
| US-4324732-A | IN PRESENCE OF TERITIARY ALIPHATIC AMINOALCOHOL AND/OR QUARTERNARY AMMONIUM COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | claimed |
| US-4288586-A | TRIMERIZATION OF ISOPHORONE DIISOCYANATE, QUATERNARY HYDROXYALKYL AMMONIUM HYDROXIDE CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | claimed |
| EP-0025926-A1 | Process for the preparation of monoaroylated 1,4-diamino anthraquinones | BAYER AG (DE) | 1981-04-01 | — | — | EP | claimed |
| US-4239661-A | HYDROXYALKYL TRIALKYLAMMONIUM HYDROXIDE | TOKYO SHIBAURA ELECTRIC CO., LTD. (JP) | 1980-12-16 | — | — | US | claimed |
| US-4172005-A | Method of etching a semiconductor substrate | TOKYO SHIBAURA ELECTRIC CO., LTD. (JP) | 1979-10-23 | — | — | US | claimed |
| US-3954650-A | Amine hardner compositions | UNION CARBIDE CORPORATION (US) | 1976-05-04 | — | — | US | claimed |