Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HRH2 | P25021 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843467 | 0.92 | KDM4E (0.60) | MGLLMEN1KMT2AHRH2HRH1 | |
| SCHEMBL10963786 | 0.86 | MEN1 (0.68) | MGLLHSD11B1MEN1KMT2AHRH2 | |
| SCHEMBL5485501 | 0.84 | KDM4E (0.54) | MEN1KMT2ARECQLCHRM2BRD4 | |
| SCHEMBL10600330 | 0.84 | HSD11B1 (0.65) | MGLLHSD11B1KDM4EHTTTDP1 | |
| SCHEMBL10968238 | 0.84 | MGLL (0.58) | MGLLHSD11B1MEN1KMT2AHRH2 | |
| SCHEMBL27453970 | 0.82 | MGLL (0.70) | MGLLHSD11B1MEN1KMT2A | |
| SCHEMBL4726771 | 0.81 | KCNH2 (0.60) | MGLLHSD11B1MEN1KMT2AHRH2 | |
| SCHEMBL9872456 | 0.80 | HSD11B1 (0.60) | MGLLHSD11B1MEN1KMT2AHRH2 | |
| SCHEMBL10966317 | 0.79 | MGLL (0.59) | MGLLHSD11B1MEN1KMT2AHRH2 | |
| SCHEMBL10965732 | 0.78 | CCR6 (0.71) | MGLLHSD11B1MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066259-B1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-10 | — | — | EP | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |
| EP-1066259-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051578-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-14 | — | — | WO | disclosed |