Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRHR | P34981 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489371 | 1.00 | ACACB (0.34) | ACACBSMN1; SMN2POLBTRHRHDAC3 | |
| SCHEMBL5495019 | 0.89 | SMN1; SMN2 (0.35) | ACACBSMN1; SMN2POLBTRHRMEN1 | |
| SCHEMBL5495013 | 0.89 | SMN1; SMN2 (0.35) | ACACBSMN1; SMN2POLBTRHRMEN1 | |
| SCHEMBL5494049 | 0.82 | DPP7 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL5494046 | 0.82 | DPP7 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL11742332 | 0.80 | L3MBTL1 (0.49) | SMN1; SMN2POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL11737947 | 0.79 | TRHR (0.38) | ACACBSMN1; SMN2POLBTRHRHDAC3 | |
| SCHEMBL5491123 | 0.78 | L3MBTL1 (0.33) | MEN1KMT2A | |
| SCHEMBL5496797 | 0.76 | L3MBTL1 (0.33) | — | |
| SCHEMBL5496795 | 0.76 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |