SCHEMBL5495059

SCHEMBL5495059

C=CCOC[C@H](CO)OC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.46
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.36
PRKCE Q02156 1/20 0.35
PRKCQ Q04759 1/20 0.35
PRKCD Q05655 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL640917 1.00 PRKCA (0.46) PRKCACA1CA2CA7CA9
SCHEMBL16001973 0.91 CA1 (0.42) PRKCACA1CA2CA7CA9
SCHEMBL13449717 0.88 CA1 (0.38) PRKCACA1CA2CA7CA9
SCHEMBL19093002 0.86 CA1 (0.39) PRKCACA1CA2CA7CA9
SCHEMBL1862658 0.85 TSHR (0.37) PRKCACA1CA2CA7CA9
SCHEMBL10956519 0.84 TDP1 (0.41) PRKCACA1CA2CA7CA9
SCHEMBL1830477 0.84 TDP1 (0.41) PRKCACA1CA2CA7CA9
SCHEMBL10632353 0.84 CA1 (0.40) PRKCACA1CA2CA7CA9
SCHEMBL11125832 0.83 PRKCA (0.38) PRKCACA1CA2CA7PRKCE
SCHEMBL10902846 0.83 PRKCA (0.43) PRKCACA1CA2CA7PRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4595681-A Administering neutral glycerolipid THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-06-17 US claimed
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS NASTECH PHARMACEUTICAL COMPANY INC. 2007-04-05 US disclosed
US-5279957-A Dna sequence no:2 WASHINGTON UNIVERSITY (US) 1994-01-18 US disclosed
US-4725588-A Alkyl phospholipid antihypertensive agents in method of lowering blood pressure THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1988-02-16 US disclosed
US-4595681-A Administering neutral glycerolipid THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS PGF, PLAT, PTAFR PRKCA 1613/4885CA1 2600/4885CA2 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.