Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496759 | 1.00 | SPHK1 (0.43) | SPHK1FKBP1AACE | |
| SCHEMBL5496756 | 1.00 | SPHK1 (0.43) | SPHK1FKBP1AACE | |
| SCHEMBL5495100 | 0.93 | SPHK1 (0.42) | SPHK1FKBP1A | |
| SCHEMBL6881305 | 0.93 | SPHK1 (0.42) | SPHK1FKBP1A | |
| SCHEMBL5495102 | 0.93 | SPHK1 (0.42) | SPHK1FKBP1A | |
| SCHEMBL15624127 | 0.92 | SPHK1 (0.41) | SPHK1FKBP1A | |
| SCHEMBL16116975 | 0.91 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL15624148 | 0.91 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL20219229 | 0.88 | SPHK1 (0.41) | SPHK1FKBP1A | |
| SCHEMBL16116962 | 0.87 | FKBP1A (0.42) | SPHK1FKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458680-A1 | PRODRUGS TO D-PROLINES | F. Hoffmann-La Roche AG (CH) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051836-A1 | PRODRUGS TO D-PROLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-26 | — | — | WO | disclosed |