Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658502 | 0.87 | HRH3 (0.48) | L3MBTL1HRH3MAPTALDH1A1KMT2A | |
| SCHEMBL7474533 | 0.83 | L3MBTL1 (0.56) | POLBL3MBTL1HRH3EPHX2MAPT | |
| SCHEMBL28579495 | 0.80 | HRH3 (0.45) | POLBL3MBTL1HRH3MAPTALDH1A1 | |
| SCHEMBL14635889 | 0.79 | ALDH1A1 (0.53) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL13873093 | 0.79 | POLB (0.51) | POLBL3MBTL1HRH3EPHX2MAPT | |
| SCHEMBL6039590 | 0.78 | KMT2A (0.46) | HRH3MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL12975402 | 0.77 | POLB (0.58) | POLBL3MBTL1EPHX2ALDH1A1KMT2A | |
| SCHEMBL10311750 | 0.77 | POLB (0.62) | POLBL3MBTL1EPHX2 | |
| SCHEMBL2422744 | 0.77 | ACE (0.48) | MAPTKMT2ARAB9ALMNA | |
| SCHEMBL2422749 | 0.77 | ACE (0.48) | MAPTKMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513814-A4 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO (JP) | 2007-03-14 | — | — | EP | disclosed |
| EP-1513814-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099787-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-04 | — | — | WO | disclosed |