Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906902 | 1.00 | SERPINE1 (0.71) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL10615730 | 1.00 | SERPINE1 (0.71) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL9617126 | 0.94 | SERPINE1 (0.75) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL5157430 | 0.89 | TSHR (0.69) | SERPINE1TSHRALDH1A1LMNATP53 | |
| SCHEMBL28503735 | 0.89 | TSHR (0.69) | SERPINE1TSHRALDH1A1LMNATP53 | |
| SCHEMBL31125331 | 0.88 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31125339 | 0.88 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31125314 | 0.88 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13422476 | 0.88 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL495935 | 0.88 | CA12 (0.67) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105848730-B | Cosmetic compositions and methods providing enhanced penetration of skin care actives | 宝洁公司 | 2019-12-13 | — | — | CN | disclosed |
| US-9149530-B2 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-8426466-B2 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20070269494-A1 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070269500-A1 | Compositions and methods for enhancing active agent absorption | NEXUS PHARMA, INC. | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269494-A1 | Compositions and methods for enhancing active agent absorption | FABP2, SLC10A2, SI | SERPINE1 489/4885CA12 274/4885CA1 346/4885 |
| US-20070269500-A1 | Compositions and methods for enhancing active agent absorption | FABP2, SLC10A2, SI | SERPINE1 489/4885CA12 274/4885CA1 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.