SCHEMBL5495712

SCHEMBL5495712

N=Nc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 6/20 0.66
ACR P10323 4/20 0.66
TMPRSS15 P98073 2/20 0.66
PARP10 Q53GL7 1/20 0.54
NSD2 O96028 1/20 0.54
F2 P00734 3/20 0.53
PRSS2 P07478 3/20 0.53
PRSS3 P35030 3/20 0.53
MAPT P10636 5/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KMT2A Q03164 4/20 0.49
HGFAC Q04756 2/20 0.49
MEN1 O00255 2/20 0.49
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3924107 0.93 PARP10 (0.59) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL70034 0.84 PARP10 (0.70) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL8205435 0.81 PARP10 (0.78) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL1870544 0.80 PARP10 (0.70) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL31888 0.80 PARP10 (0.70) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL27279499 0.80 MAPT (0.66) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL14130027 0.80 MAPT (0.66) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL20008706 0.79 PRSS1 (1.00) PRSS1ACRTMPRSS15F2PRSS2
Terephthalic Acid SCHEMBL28437942 0.79 PARP10 (0.63) PRSS1ACRTMPRSS15PARP10NSD2
SCHEMBL68278 0.79 PARP10 (0.63) PRSS1ACRTMPRSS15PARP10NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007107775-A2 PREPARATION OF OLIGONUCLEOTIDES WITH PHOTOSWITCHABLE PROPERTIES THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2007-09-27 WO disclosed