Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594358 | 0.80 | MEN1 (0.56) | KDM4EALDH1A1HPGDFOLH1MEN1 | |
| SCHEMBL5495740 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL10773951 | 0.79 | MCL1 (0.56) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL10774806 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL7594375 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL7492988 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL10775994 | 0.73 | MCL1 (0.58) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL10770989 | 0.73 | PDE9A (0.55) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL11546524 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1HPGDFOLH1MCL1 | |
| SCHEMBL87871 | 0.72 | KDM4E (0.65) | KDM4EALDH1A1HPGDFOLH1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010428-A1 | Inhibitors of signal transduction and activator of transcription 3 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2007-01-11 | — | — | US | claimed |
| US-20070010428-A1 | Inhibitors of signal transduction and activator of transcription 3 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2007-01-11 | — | — | US | disclosed |