Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351116 | 0.86 | MAP2 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7559737 | 0.85 | TUBB4A (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7676133 | 0.82 | GAA (0.55) | KDM4EALDH1A1MEN1KMT2ATUBB4A | |
| SCHEMBL7594358 | 0.82 | MEN1 (0.56) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2345966 | 0.81 | MAPT (0.60) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10774806 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10773951 | 0.78 | MCL1 (0.56) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5495745 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9335819 | 0.76 | MEN1 (0.69) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10761140 | 0.76 | TP53 (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022576-A2 | 3-SUBSTITUTED INDOLE CARBOHYDRAZIDES USEFUL AS CELL PROLIFERATION AND ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-21 | — | — | WO | disclosed |