Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497802 | 0.94 | MAPT (0.46) | HTTLMNAMAPTHDAC4HDAC2 | |
| SCHEMBL14613677 | 0.92 | MAPT (0.44) | HTTLMNAMAPTHDAC4HDAC2 | |
| SCHEMBL27501679 | 0.82 | MEN1 (0.50) | HTTLMNAMAPTHDAC4HDAC2 | |
| SCHEMBL10057985 | 0.80 | ALOX5 (0.49) | HTTLMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL1312333 | 0.78 | MAOB (0.49) | HTTLMNAMAPTHDAC4HDAC2 | |
| SCHEMBL56762 | 0.78 | MEN1 (0.60) | HTTLMNAMAPTHDAC4HDAC2 | |
| Anthraquinone SCHEMBL28835137 | 0.78 | MEN1 (0.60) | HTTLMNAMAPTHDAC4HDAC2 | |
| SCHEMBL19810034 | 0.77 | ESR1 (0.48) | HTTLMNAMAPTHPGDMAOB | |
| SCHEMBL29750116 | 0.76 | MEN1 (0.57) | HTTLMNAMAPTHDAC4HDAC2 | |
| SCHEMBL5497888 | 0.75 | BACE1 (0.38) | HTTLMNAMAPTHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999256-B1 | COMPOUNDS FOR ORGANIC EL ELEMENT AND ORGANIC EL ELEMENT | TDK CORP (JP) | 2007-02-14 | — | — | EP | disclosed |
| US-6399223-B1 | Compound for use in organic EL device and organic EL device | TDK CORPORATION (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-0999256-A1 | COMPOUNDS FOR ORGANIC EL ELEMENT AND ORGANIC EL ELEMENT | TDK Corporation (JP) | 2000-05-10 | — | — | EP | disclosed |