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Sugi Predict / Compounds / SCHEMBL2021385

SCHEMBL2021385

SCHEMBL2021385

NC(=O)C[C@H](NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ MAPT P10636 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ ITGB2 P05107 2/20 0.47
▸ ICAM1 P05362 2/20 0.47
▸ ITGAL P20701 2/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.42
▸ CA2 P00918 4/20 0.41
▸ CA1 P00915 3/20 0.41
▸ KMT2A Q03164 3/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KIF11 P52732 3/20 0.39
▸ MMP2 P08253 2/20 0.38
▸ MMP9 P14780 2/20 0.38
▸ CYP2C19 P33261 1/20 0.37
▸ DNMT1 P26358 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2021383 1.00 ALDH1A1 (0.48) ALDH1A1RAB9AMAPTKDM4EITGB2
SCHEMBL28694554 1.00 ALDH1A1 (0.48) ALDH1A1RAB9AMAPTKDM4EITGB2
SCHEMBL6137131 0.91 KIF11 (0.47) ALDH1A1RAB9AMAPTKDM4EITGB2
SCHEMBL6137134 0.91 KIF11 (0.47) ALDH1A1RAB9AMAPTKDM4EITGB2
SCHEMBL7224170 0.86 MAPT (0.45) ALDH1A1MAPTKDM4ENPSR1CA2
SCHEMBL5495801 0.84 KMT2A (0.52) NPSR1CA2CA1KMT2AKIF11
SCHEMBL2021994 0.84 KMT2A (0.52) NPSR1CA2CA1KMT2AKIF11
SCHEMBL27717200 0.84 KMT2A (0.52) NPSR1CA2CA1KMT2AKIF11
SCHEMBL30510931 0.83 NPSR1 (0.42) ALDH1A1MAPTNPSR1KIF11CYP2C19
SCHEMBL27429530 0.83 PTPN1 (0.41) ALDH1A1RAB9AMAPTKDM4EITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024316-A 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof 南开大学 2023-11-10 — — CN claimed
CN-114163354-B Preparation method of N-fluorenylmethoxycarbonyl-N-trityl-L-asparagine 常州吉恩药业有限公司 2023-05-05 — — CN claimed
CN-114163354-A Preparation method of N-fluorenylmethoxycarbonyl-N-trityl-L-asparagine 常州吉恩药业有限公司 2022-03-11 — — CN claimed
EP-2872479-B1 METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS HEIDELBERG PHARMA GMBH (DE) 2016-06-08 — — EP claimed
US-5618825-A ENZYME INHIBITORS; ANTICOAGULANTS; VISION DISORDERS PHARMACOPEIA, INC. (US) 1997-04-08 — — US claimed
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 JANSSEN PHARMACEUTICA NV (BE) 2026-01-22 — — US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
US-20260000659-A1 LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR JANSSEN BIOTECH INC (US) 2026-01-01 — — US disclosed
US-12478617-B2 Lipidated peptide inhibitors of interleukin-23 receptor JANSSEN BIOTECH, INC. (US) 2025-11-25 — — US disclosed
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 — — WO disclosed
CN-119677795-A Amphiphilic poly (amino acid) linear block copolymers and nanoparticles thereof for drug delivery applications 纳诺瑟拉生物科学股份有限公司 2025-03-21 — — CN disclosed
EP-4469468-A1 PROCESS FOR THE PREPARATION OF LINACLOTIDE Fresenius Kabi iPSUM S.r.l. (IT) 2024-12-04 — — EP disclosed
US-5734054-A Hydroxy-amino acid amides PHARMACOPEIA, INC. (US) 1998-03-31 — — US disclosed
WO-1997027315-A1 COMBINATORIAL HYDROXYPROPYLAMINE LIBRARY PHARMACOPEIA, INC. (US) 1997-07-31 — — WO disclosed
US-5620955-A SYNTHETIC PEPTIDE DERIVATIVES; INHIBIT GROWTH OF SMALL CELL LUNG CANCER OR PANCREATIC CELLS PEPTIDE TECHNOLOGIES CORPORATION (US) 1997-04-15 — — US disclosed
US-5618825-A ENZYME INHIBITORS; ANTICOAGULANTS; VISION DISORDERS PHARMACOPEIA, INC. (US) 1997-04-08 — — US disclosed
EP-0659181-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1995-06-28 — — EP disclosed
WO-1995000542-A1 BOMBESIN RECEPTOR ANTAGONISTS AND USES THEREOF PEPTIDE TECHNOLOGIES CORPORATION (US) 1995-01-05 — — WO disclosed
WO-1994005639-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-03-17 — — WO disclosed
WO-1992016501-A1 TETRAHYDROXYALKANE DERIVATIVES AS INHIBITORS OF HIV ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1992-10-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 IL23R, IL17A, IL36G ALDH1A1 4865/4885RAB9A 1518/4885MAPT 3322/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 ALDH1A1 2330/4885RAB9A 1211/4885MAPT 4146/4885
US-20260000659-A1 LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL36G, IL15RA ALDH1A1 3214/4885RAB9A 4114/4885MAPT 3683/4885
US-12478617-B2 Lipidated peptide inhibitors of interleukin-23 receptor IL23R, IL1RN, IL36G ALDH1A1 4010/4885RAB9A 2215/4885MAPT 2026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.