Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157150 | 0.69 | CALM1 (0.32) | — | |
| SCHEMBL493721 | 0.64 | — | — | |
| SCHEMBL3818677 | 0.57 | — | — | |
| SCHEMBL2502150 | 0.57 | — | — | |
| SCHEMBL7600 | 0.56 | — | — | |
| SCHEMBL3991516 | 0.56 | CYP2A6 (0.31) | — | |
| SCHEMBL5888763 | 0.55 | — | — | |
| SCHEMBL8711 | 0.54 | — | — | |
| SCHEMBL14417491 | 0.54 | ABCG2 (1.00) | ABCG2ITGB2ICAM1ITGAL | |
| SCHEMBL12430552 | 0.54 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747213-A1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2007-01-31 | — | — | EP | claimed |
| WO-2005116007-A1 | NOVEL 7,7-DISUBSTITUTED DERIVATIVES OF (5H,9H)-6,8-DIOXABENZOCYCLOHEPTENE, PREPARATION METHOD THEREOF AND USE OF SAME IN THE SYNTHESIS OF NON-STEROIDAL VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-12-08 | — | — | WO | claimed |
| US-7019055-B2 | Stabilization of polymers after exposure to oxidation | WANG QI | 2006-03-28 | — | — | US | disclosed |
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |