Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445136 | 0.86 | GPR35 (0.64) | GPR35ERN1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL30408060 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TSHRTAAR1L3MBTL1HPGD | |
| SCHEMBL1811434 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TSHRTAAR1L3MBTL1HPGD | |
| SCHEMBL5595098 | 0.83 | GPR35 (0.60) | GPR35ERN1ALDH1A1TSHRTDP1 | |
| SCHEMBL11306648 | 0.82 | GPR35 (0.69) | GPR35ERN1ALDH1A1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3652038 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTAAR1L3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL31250676 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTAAR1L3MBTL1HPGD | |
| SCHEMBL9820277 | 0.81 | ALDH1A1 (0.46) | GPR35ALDH1A1TSHRTAAR1TDP1 | |
| SCHEMBL4854222 | 0.80 | GPR35 (0.67) | GPR35ERN1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27671751 | 0.80 | GPR35 (0.67) | GPR35ERN1ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169759-B1 | Tetrapeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-01-30 | — | — | US | disclosed |