SCHEMBL5496547

SCHEMBL5496547

CCCCCCNC(=O)NCCCCCC1CCCCC1

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 16/20 0.65
EPHX2 P34913 2/20 0.65
NAAA Q02083 1/20 0.59
SIGMAR1 Q99720 1/20 0.54
METAP2 P50579 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25834507 0.86 CASP2 (0.56) EPHX1EPHX2NAAAMETAP2
SCHEMBL22260401 0.86 CASP2 (0.56) EPHX1EPHX2NAAAMETAP2
Cyclohexane SCHEMBL5496549 0.84 EPHX1 (0.86) EPHX1EPHX2NAAA
Bicarbonate SCHEMBL4782415 0.83 CYP1A2 (0.65) EPHX1NAAASIGMAR1
Bicarbonate SCHEMBL9562968 0.83 CYP1A2 (0.65) EPHX1NAAASIGMAR1
SCHEMBL8847500 0.83 CASP2 (0.59) EPHX1EPHX2NAAAMETAP2
SCHEMBL24115530 0.81 SIGMAR1 (0.59) EPHX1EPHX2NAAASIGMAR1
Urea SCHEMBL1837240 0.81 CYP1A2 (0.63) EPHX1EPHX2NAAASIGMAR1METAP2
Sulfuric Acid SCHEMBL3813493 0.81 CYP1A2 (0.63) EPHX1EPHX2NAAASIGMAR1METAP2
SCHEMBL22651943 0.81 SIGMAR1 (0.63) EPHX1EPHX2NAAASIGMAR1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1749038-A1 N-ACYLUREA COMPOUNDS FOR PREPARING POLYURETHANES Alcan Packaging Italia S.r.l. (IT) 2007-02-07 EP disclosed
WO-2005118666-A1 N-ACYLUREA COMPOUNDS FOR PREPARING POLYURETHANES ALCAN PACKAGING ITALIA S.R.L. (IT) 2005-12-15 WO disclosed