Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.59 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 9/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913895 | 0.86 | BACE1 (0.57) | CTSDBACE1BACE2 | |
| SCHEMBL29601744 | 0.86 | BACE1 (0.60) | CTSDBACE1BACE2 | |
| SCHEMBL30130747 | 0.84 | BACE1 (0.62) | CTSDBACE1BACE2 | |
| SCHEMBL10790323 | 0.84 | BACE1 (0.60) | CTSDBACE1BACE2 | |
| SCHEMBL30051333 | 0.84 | BACE1 (0.58) | CTSDBACE1 | |
| SCHEMBL7323888 | 0.83 | FCER2 (0.58) | CTSDBACE1BACE2 | |
| SCHEMBL30872253 | 0.82 | BACE1 (0.65) | CTSDBACE1BACE2 | |
| Hydrochloric Acid SCHEMBL8615559 | 0.82 | MMP8 (0.59) | PSMB1PSMB5PSMB2ANPEP | |
| SCHEMBL14341926 | 0.82 | BACE1 (0.62) | CTSDBACE1BACE2 | |
| SCHEMBL8614468 | 0.82 | MMP8 (0.61) | PSMB1PSMB5PSMB2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346041-B1 | THERAPEUTIC AGENTS AND METHODS OF USE THEREOF FOR TREATING AN AMYLOIDOGENIC DISEASE | PRAECIS PHARM INC (US) | 2007-02-28 | — | — | EP | claimed |