Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496981 | 1.00 | TSHR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9997541 | 0.83 | TSHR (0.36) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9997540 | 0.83 | TSHR (0.36) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL10785233 | 0.82 | TSHR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL10785230 | 0.82 | TSHR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9997687 | 0.80 | TSHR (0.42) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9997689 | 0.80 | TSHR (0.42) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9998010 | 0.79 | ALDH1A1 (0.38) | TSHRALDH1A1LMNAGRIK1 | |
| SCHEMBL9998008 | 0.79 | ALDH1A1 (0.38) | TSHRALDH1A1LMNAGRIK1 | |
| SCHEMBL10782842 | 0.78 | ALDH1A1 (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574509-B1 | PROCESS FOR THE PRODUCTION OF 1-ACETOXY-3-(SUBSTITUTED PHENYL)PROPENES | UBE INDUSTRIES (JP) | 2007-06-13 | — | — | EP | claimed |
| US-7173148-B2 | Process for producing 1-acetoxy-3-(substituted phenyl)propene compound | UBE INDUSTRIES, LTD. (JP) | 2007-02-06 | — | — | US | claimed |
| US-20060069273-A1 | Process for producing 1-acetoxy-3-(substituded phenyl) propenes | UBE INDUSTRIES, LTD. (JP) | 2006-03-30 | — | — | US | claimed |
| EP-1574509-A1 | PROCESS FOR THE PRODUCTION OF 1-ACETOXY-3-(SUBSTITUTED PHENYL)PROPENES | Ube Industries, Ltd. (JP) | 2005-09-14 | — | — | EP | claimed |
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-1609775-B1 | 1-acetoxy-3-(substituted phenyl) propen compounds useful as an intermediate material | UBE INDUSTRIES (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1574509-B1 | PROCESS FOR THE PRODUCTION OF 1-ACETOXY-3-(SUBSTITUTED PHENYL)PROPENES | UBE INDUSTRIES (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-7173148-B2 | Process for producing 1-acetoxy-3-(substituted phenyl)propene compound | UBE INDUSTRIES, LTD. (JP) | 2007-02-06 | — | — | US | disclosed |
| US-20060069273-A1 | Process for producing 1-acetoxy-3-(substituded phenyl) propenes | UBE INDUSTRIES, LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| US-20060004213-A1 | 1-Acetoxy-3-(substituted phenyl)propene compounds | UBE INDUSTRIES, LTD., A CORPORATION OF JAPAN (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1609775-A2 | 1-acetoxy-3-(substituted phenyl) propen compounds useful as an intermediate material | Ube Industries, Ltd. (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-1574509-A1 | PROCESS FOR THE PRODUCTION OF 1-ACETOXY-3-(SUBSTITUTED PHENYL)PROPENES | Ube Industries, Ltd. (JP) | 2005-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004213-A1 | 1-Acetoxy-3-(substituted phenyl)propene compounds | AKR1C3, P4HA1, AKR1C1 | TSHR 3325/4885CHRM2 772/4885CHRM4 2144/4885 |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | CBR1, CYP1B1, CYP2F1 | TSHR 621/4885CHRM2 1299/4885CHRM4 2767/4885 |
| US-20060069273-A1 | Process for producing 1-acetoxy-3-(substituded phenyl) propenes | AKR1C4, PAH, AKR1C3 | TSHR 1110/4885CHRM2 2415/4885CHRM4 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.