Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497074 | 0.88 | MAPK14 (0.48) | RAB9APOLBPKMMAPK14 | |
| SCHEMBL5497956 | 0.81 | KMT2A (0.49) | KMT2AMMP2MMP9L3MBTL1ALDH1A1 | |
| SCHEMBL9294202 | 0.74 | KMT2A (0.51) | KMT2AMMP2MMP9L3MBTL1CA2 | |
| SCHEMBL20840361 | 0.74 | KMT2A (0.51) | KMT2AMMP2MMP9L3MBTL1CA2 | |
| SCHEMBL5595918 | 0.74 | KMT2A (0.51) | KMT2AMMP2MMP9L3MBTL1CA2 | |
| SCHEMBL28975404 | 0.72 | KMT2A (0.47) | KMT2AMMP2MMP9L3MBTL1ALDH1A1 | |
| SCHEMBL28711052 | 0.72 | KMT2A (0.50) | RAB9APOLBKMT2AMMP2MMP9 | |
| SCHEMBL2247510 | 0.72 | FOLH1 (0.49) | KMT2AMMP2MMP9ALDH1A1HTT | |
| SCHEMBL30047206 | 0.72 | HTT (0.50) | RAB9APOLBKMT2APKMALDH1A1 | |
| SCHEMBL30046876 | 0.72 | HTT (0.50) | RAB9APOLBKMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868535-B9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2007-05-09 | — | — | EP | claimed |
| EP-0868535-B2 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2006-01-04 | — | — | EP | claimed |
| EP-0868535-B1 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | RAPIGENE INC (US) | 2000-04-12 | — | — | EP | claimed |