Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 14/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497076 | 0.88 | RAB9A (0.44) | MAPK14POLBRAB9APKM | |
| SCHEMBL5497952 | 0.80 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL30047206 | 0.74 | HTT (0.50) | POLBRAB9APKM | |
| SCHEMBL30046876 | 0.74 | HTT (0.50) | POLBRAB9APKM | |
| SCHEMBL3130610 | 0.73 | RAB9A (0.68) | POLBRAB9A | |
| SCHEMBL25329657 | 0.72 | APEX1 (0.43) | FOLH1 | |
| SCHEMBL4821084 | 0.72 | CYP1A2 (0.46) | FOLH1 | |
| SCHEMBL11202913 | 0.72 | DGAT1 (0.48) | POLBRAB9APKM | |
| SCHEMBL11202915 | 0.72 | DGAT1 (0.48) | POLBRAB9APKM | |
| SCHEMBL7582068 | 0.71 | ULK1 (0.54) | POLBRAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868535-B9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2007-05-09 | — | — | EP | claimed |
| EP-0868535-B2 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2006-01-04 | — | — | EP | claimed |
| EP-0868535-B1 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | RAPIGENE INC (US) | 2000-04-12 | — | — | EP | claimed |