Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168098 | 0.93 | AR (0.65) | ARPGRSLC22A12POLBGAA | |
| SCHEMBL4174837 | 0.91 | AR (0.58) | ARPGRSLC22A12POLBGAA | |
| SCHEMBL4181110 | 0.85 | AR (0.64) | ARPGRSLC22A12POLBGAA | |
| SCHEMBL8543199 | 0.83 | AR (0.62) | ARPGRSLC22A12GAASMN1; SMN2 | |
| SCHEMBL4178023 | 0.81 | AR (0.74) | ARPGRSLC22A12POLBGAA | |
| SCHEMBL20510909 | 0.81 | AR (0.70) | ARPGRPOLBGAAESRRA | |
| SCHEMBL966608 | 0.80 | AR (0.57) | ARPGRSLC22A12POLBGAA | |
| SCHEMBL756234 | 0.79 | AR (0.62) | ARPGRSLC22A12POLBGAA | |
| SCHEMBL8566836 | 0.78 | AR (0.43) | ARPGRPOLBGAASMN1; SMN2 | |
| SCHEMBL7073821 | 0.76 | AR (0.55) | ARPGRSLC22A12GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | claimed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | claimed |