SCHEMBL20510909

SCHEMBL20510909

COc1cccc(OC)c1Oc1ccc(C#N)c(C#N)c1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AR P10275 11/20 0.70
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
PGR P06401 1/20 0.48
CYP19A1 P11511 1/20 0.48
IMPDH2 P12268 1/20 0.47
IMPDH1 P20839 1/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
ESRRA P11474 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28984282 0.91 AR (0.59) ARPOLBGAACYP19A1IMPDH2
SCHEMBL4168098 0.86 AR (0.65) ARPOLBGAAPGRESRRA
SCHEMBL4174826 0.83 AR (1.00) AR
SCHEMBL9746262 0.83 ALDH1A1 (0.51) ARPOLBGAACYP19A1ALDH1A1
SCHEMBL9747084 0.83 ALDH1A1 (0.51) ARPOLBGAACYP19A1ALDH1A1
SCHEMBL8630217 0.81 AR (0.58) ARPOLBGAACYP19A1
SCHEMBL5497091 0.81 AR (0.58) ARPOLBGAAPGRESRRA
SCHEMBL23795062 0.80 AR (0.55) ARCYP19A1
SCHEMBL522176 0.80 AR (0.68) ARCYP19A1ALDH1A1
SCHEMBL1940627 0.79 AR (0.57) ARPOLBGAACYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2020-04-30 US disclosed
EP-3601215-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M Innovative Properties Company (US) 2020-02-05 EP disclosed
WO-2018175025-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES PNN, RPN1, DCXR AR 2001/4885POLB 1900/4885GAA 2465/4885
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles PNN, RPN1, DCXR AR 2001/4885POLB 1900/4885GAA 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.