Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179186 | 0.82 | RAB9A (0.40) | ARMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL27659861 | 0.80 | L3MBTL1 (0.44) | MAPTGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL4174837 | 0.80 | AR (0.58) | ARGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL5497091 | 0.78 | AR (0.58) | ARGAAPOLBPGRSMN1; SMN2 | |
| SCHEMBL8561327 | 0.76 | POLB (0.73) | ARGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL14861184 | 0.75 | SLC22A12 (0.43) | ARMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL27918629 | 0.74 | CYP19A1 (0.50) | ARALDH1A1HPGDPGRPDE4B | |
| SCHEMBL4168823 | 0.74 | AR (0.46) | ARMAPTGAAPOLBKDM4E | |
| SCHEMBL22867963 | 0.73 | AR (0.66) | ARGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL4168098 | 0.72 | AR (0.65) | ARGAAPOLBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |