Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236614 | 0.84 | SLC9A1 (0.37) | ALDH1A1SLC9A1MEN1KMT2AHTT | |
| SCHEMBL2784532 | 0.81 | SLC9A1 (0.40) | ALDH1A1SLC9A1KDM4EHSD17B10TDP1 | |
| SCHEMBL28905062 | 0.80 | SLC9A1 (0.41) | ALDH1A1SLC9A1CYP1A2CYP2D6 | |
| SCHEMBL9581979 | 0.79 | — | — | |
| SCHEMBL2948314 | 0.79 | KDM4E (0.38) | ALDH1A1SMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL6227403 | 0.79 | L3MBTL1 (0.34) | ALDH1A1SMN1; SMN2HTTLMNAKDM4E | |
| SCHEMBL6230861 | 0.79 | — | — | |
| SCHEMBL3086235 | 0.78 | TP53 (0.38) | KMT2ASMN1; SMN2HTTLMNAKDM4E | |
| SCHEMBL11719143 | 0.78 | SLC9A1 (0.43) | ALDH1A1SLC9A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8699910 | 0.78 | SLC9A1 (0.43) | ALDH1A1SLC9A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072467-B | Substituted guanidino-containing derivative and application thereof in preparing osteoclast differentiation inhibitor | 南方医科大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113072467-A | Substituted guanidino-containing derivative and application thereof in preparing osteoclast differentiation inhibitor | 南方医科大学 | 2021-07-06 | — | — | CN | claimed |
| CN-112521382-A | Aloe-emodin thiazolidinedione compound and preparation method and application thereof | 西南大学 | 2021-03-19 | — | — | CN | claimed |
| CN-113072467-B | Substituted guanidino-containing derivative and application thereof in preparing osteoclast differentiation inhibitor | 南方医科大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-113072467-A | Substituted guanidino-containing derivative and application thereof in preparing osteoclast differentiation inhibitor | 南方医科大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-112521382-A | Aloe-emodin thiazolidinedione compound and preparation method and application thereof | 西南大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-112218852-A | Oxidized bis (3-indolyl) methane and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2021-01-12 | — | — | CN | disclosed |
| CN-106928150-B | Acrylamide aniline derivative and pharmaceutical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2020-07-31 | — | — | CN | disclosed |
| US-10342796-B2 | Acrylanilide derivative, preparation method, and applications thereof in pharmacy | ANCUREALL PHARMACEUTICAL (SHANGHAI) CO., LTD. (CN) | 2019-07-09 | — | — | US | disclosed |
| US-20190015413-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD, AND APPLICATIONS THEREOF IN PHARMACY | ANCUREALL PHARMACEUTICAL (SHANGHAI) CO., LTD. (CN) | 2019-01-17 | — | — | US | disclosed |
| EP-3398939-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2018-11-07 | — | — | EP | disclosed |
| EP-0435179-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0426043-A2 | Silver halide color photographic material and method for forming color image | Fuji Photo Film Co., Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |
| US-4966983-A | PRESSURE OR HEAT SENSITIVE ELEMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4940703-A | Spirocyclic compounds incorporating five-membered rings with two heteroatoms for treating psychotic disorders, etc. | MERCK SHARP & DOHME LIMITED (GB) | 1990-07-10 | — | — | US | disclosed |
| EP-0337547-A1 | Spirocyclic compounds incorporating five-membered rings with two heteroatoms | MERCK SHARP & DOHME LTD. (GB) | 1989-10-18 | — | — | EP | disclosed |
| US-4841050-A | Carbazole containing benzopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0236973-B1 | BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |
| EP-0236973-A2 | Benzopyranes and their use in a recording system | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0105397-B1 | SULPHURIC INDOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1986-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342796-B2 | Acrylanilide derivative, preparation method, and applications thereof in pharmacy | EGFR, ABL1, CSNK1A1 | ALDH1A1 2848/4885SLC9A1 2457/4885NR4A2 3847/4885 |
| US-20190015413-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD, AND APPLICATIONS THEREOF IN PHARMACY | EGFR, ABL1, CSNK1A1 | ALDH1A1 2848/4885SLC9A1 2457/4885NR4A2 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.