Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699438 | 1.00 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1AHTR2CHTR2B | |
| SCHEMBL2699441 | 1.00 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1AHTR2CHTR2B | |
| SCHEMBL549760 | 1.00 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1AHTR2CHTR2B | |
| SCHEMBL549289 | 1.00 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1AHTR2CHTR2B | |
| SCHEMBL549288 | 1.00 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1AHTR2CHTR2B | |
| SCHEMBL549967 | 0.88 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A | |
| SCHEMBL550441 | 0.88 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A | |
| SCHEMBL550442 | 0.88 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A | |
| SCHEMBL549968 | 0.88 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A | |
| SCHEMBL2699812 | 0.88 | HSD11B1 (0.44) | HSD11B1NOTUMHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110581-B2 | Lactam compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2012-02-07 | — | — | US | claimed |