Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861748 | 0.82 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1NPSR1TSHR | |
| SCHEMBL3837976 | 0.77 | HDAC3 (0.56) | RAB9ASMN1; SMN2NPC1NPSR1TSHR | |
| SCHEMBL6697985 | 0.76 | TSHR (0.55) | RAB9ASMN1; SMN2NPC1NPSR1TSHR | |
| SCHEMBL14336224 | 0.74 | SLC9A1 (0.50) | RAB9ASMN1; SMN2NPC1MAPTUSP2 | |
| SCHEMBL5497686 | 0.73 | HTT (0.43) | RAB9ASMN1; SMN2NPC1NPSR1TSHR | |
| SCHEMBL818764 | 0.73 | TSHR (0.58) | RAB9ASMN1; SMN2NPC1NPSR1TSHR | |
| SCHEMBL14153147 | 0.72 | NPC1 (0.53) | RAB9ASMN1; SMN2NPC1NPSR1TSHR | |
| SCHEMBL13604195 | 0.72 | EGLN3 (0.55) | RAB9ASMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL2531577 | 0.70 | TSHR (0.56) | TSHRALDH1A1 | |
| SCHEMBL17103166 | 0.70 | TSHR (0.58) | RAB9ASMN1; SMN2NPC1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279507-B2 | Contact lenses | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2007-10-09 | — | — | US | disclosed |
| US-20050148682-A1 | Interpenetrating polymer network hydrophilic hydrogels for contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2005-07-07 | — | — | US | disclosed |
| EP-1095076-A4 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | SUNSOFT CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| US-20010044482-A1 | Interpenetrating polymer network hydrophilic hydrogels for contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2001-11-22 | — | — | US | disclosed |
| EP-1095076-A1 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | Sunsoft Corporation (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002937-A1 | INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS | SUNSOFT CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5684059-A | FLUOROMONOMER, HYDROXYALKYL ACRYLATE OR METHACRYLATE, N-VINYL LACTAM, SULFONIC ACID MONOMER | OPTIMERS, INC. | 1997-11-04 | — | — | US | disclosed |
| EP-0253515-B1 | Fluorine containing soft contact lens hydrogels | OPTIMERS INC (US) | 1995-08-09 | — | — | EP | disclosed |
| WO-1992011300-A1 | FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS | SALAMONE JOSEPH C (US) | 1992-07-09 | — | — | WO | disclosed |
| US-4990582-A | Wettable, oxygen permeable resistant to protein deposits | OPTIMERS, INC. | 1991-02-05 | — | — | US | disclosed |